None listed
Conditions
Brief summary
Cataracts are easily treated with surgery, but there is a small risk of damaging the endothelial cells of the cornea which can lead to corneal swelling, affecting vision. Certain conditions such as traumatic cataract increase this risk. The Quatera 700 is an innovative machine used for cataract surgery, designed to cause less damage to the corneal endothelium. As such, we aim to document recovery of 10 complex surgery cataract surgery cases performed using this Quatera 700, in particular the change in cell count of the corneal endothelium. Patients who consent to the project will undergo routine care for their complex cataracts, but will attend additional appointments to measure the endothelial cell count (non-invasive imaging), which has minimal to no adverse effects.
Interventions
Complex cataract surgery with Zeiss Quatera 700
Cataract surgery will be performed by an Ophthalmologist at the Broome Regional Hospital with the Zeiss Quatera 700 machine. Patients will have cataract surgery performed with Quatera 700 regardless of their participation in this study. The Zeiss Quatera 700 is an approved cataract surgery machine, therefore Ophthalmologists require no additional training to use it. However, a Zeiss rep was present for the first few surgical lists for each surgeon
Complex cataract surgery with Zeiss Quatera 700 Cataract surgery will be performed by an Ophthalmologist at the Broome Regional Hospital with the Zeiss Quatera 700 machine. Patients will have cataract surgery performed with Quatera 700 regardless of their participation in this study. The Zeiss Quatera 700 is an approved cataract surgery machine, therefore Ophthalmologists require no additional training to use it. However, a Zeiss rep was present for the first few surgical lists for each surgeon in April and May 2023 to troubleshoot and help establish surgeon preference parameters. Under routine care, patients undergoing cataract surgery attend one pre-operative appointment and post-operatively will have a follow-up the next day and a month later. As part of this study, participants will be asked to attend an additional three-month follow-up visit. These clinic visits will be conducted face-to-face by Lions Outback Vision Ophthalmologists or Registered Medical Officers, although the doctor may not be the one that performed the surgery. Further details including procedures undertaken at these visits are outlined below. Visit 1, 60 minutes at LOV clinic, pre-operative: Visual acuity - aided, unaided, pinhole; intraocular pressure (IOP); biometry; slit lamp examination; fundus examination, specular microscopy. Surgical visit, up to 30 minutes for surgery and 4-6 hours for hospital visit at Broome Hospital: Cataract surgery performed by an Ophthalmologist at the Broome Regional Hospital with the Zeiss Quatera 700 machine. Visit 2, 30 minutes at LOV clinic, 1 day post-operative: Uncorrected distance visual acuity (UDVA), IOP, pachymetry. Visit 3, 45 minutes at LOV clinic, 1 Month post-operative: UDVA, IOP, optical coherence tomography (OCT) macula, pachymetry, specular microscopy. Visit 4, 45 minutes at LOV clinic, 3 Month post-operative: UDVA, IOP, OCT macula, pachymetry, specular microscopy. Adherence to the intervention will be assessed through review of the electronic medical record.
Sponsors
Dr Angus Turner, Lions Eye Institute
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
Adults (18 years and over) with complex cataract, defined as meeting any of the following criteria: a) those with cataract following traumatic ocular injury resulting in zonular dehiscence; b) those with pseudoexfoliation syndrome; c) those with dense cataract; d) those with short anterior chamber depth (less than 2.5mm); e) those with small pupils (less than 4mm diamter when dilated)
Exclusion criteria
1. Those with pre-operative central endothelial cell count of less than 1500 cells/mm2 2. Those with prior corneal disease including corneal scars, severe dry eye syndrome 3. Those with prior pupillary abnormalities 4. Those with very guarded visual prognosis, e.g. no perception of light and/or relative afferent pupil defect
Outcome results
None listed