None listed
Conditions
Brief summary
This study aims to evaluate the efficacy of a non-invasive photobiomodulation diode laser in symptomatic irreversible pulpitis by assessing Inflammatory biomarkers S100 A8/A9 protein in pulp blood (PB) and gingival cervical fluids (GCF) before and after intervention
Interventions
Participants in the intervention group will receive PBM only receive one of either wavelength treatment
A single intervention session last about 1 min , a postgraduate student in the Doctor of Clinical Dentistry program will be administering the intervetion who is a registered dentist
The gingival tissue will not be in the line of irradiation
Photobiomodulation - PBM
The laser irradiation will be performed by placing the optic fibre tip in line with the occlusal access cavity of the tooth
Participants in the intervention group will receive PBM only receive one of either wavelength treatment A single intervention session last about 1 min , a postgraduate student in the Doctor of Clinical Dentistry program will be administering the intervetion who is a registered dentist The gingival tissue will not be in the line of irradiation Photobiomodulation - PBM The laser irradiation will be performed by placing the optic fibre tip in line with the occlusal access cavity of the tooth with exposed pulp tissue, and the irradiation time will be 60 sec. Gingival tissue will not in the line of irradiation. The power output of two wavelengths has been assessed using a power meter (Ophir Optronics, MKS Instruments Inc, Utah, US). The 808 nm PBM will be administered with a power density of 0.5 W/cm² and an energy density of 30 J/cm². The 660 nm PBM will be applied with a power density of 0.28 W/cm² and an energy density of 16.8 J/cm².
Sponsors
Griffith University
Study design
Allocation
Randomised controlled trial
Primary purpose
Treatment
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Healthy volunteers
No
Inclusion criteria
Patients diagnosed with symptomatic irreversible pulpitis from the age range of 18 to 80 years will be included in this study. Patients will be required to describe the pain using a visual analogue scale (1-10), and pain levels will be assessed by the operator using various assessment tools, Patients with a pain score of 7/10 and above were included in this study. The diagnosis of symptomatic irreversible pulpitis (SIP) will follow the American Association of Endodontists (AAE) Glossary of Endodontic Terms
Exclusion criteria
Patients with periodontal disease, cancer, immunocompromised condition, intake of opioid medication, internal or external root reporting, teeth with a history of trauma, root fracture and teeth with open apices and apical radiolucency were excluded from the study.
Outcome results
None listed