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Restricting and then resuming certain behaviors and the effects on symptoms of anxiety and depression

Things You Do (TYD) RCT #3: Randomised Controlled Trial of the Restriction/Resume Method Comparing the Effect of TYD vs. Waitlist Control (“Restriction/Resume RCT”) on Symptoms of Anxiety and Depression in Healthy Adults

Status
Completed
Phases
Unknown
Study type
Interventional
Source
ANZCTR
Registry ID
ACTRN12624001491550
Enrollment
70
Registered
2024-12-20
Start date
2025-02-03
Completion date
2025-02-17
Last updated
2026-03-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

The proposed project further extends our systematic efforts to understand the relationship between symptoms of anxiety and depression, and daily actions (i.e., thoughts and behaviours - "Things You Do"). The primary objective of this trial is to compare the effects of restricting and then resuming the Things You DO (TYD). The research design is a parallel group randomised controlled trial. Participants (n = 60) will be Australian adults assigned to either the intervention group (behaviour restricted and then resumed) or a control group. Based on our earlier studies, the primary hypothesis is that restricting and then increasing the frequency of TYD actions will result in significantly greater increases and then reductions in symptoms of anxiety and depression, relative to a control condition.

Interventions

The research design is a parallel group randomised controlled trial. Applicants will be randomly allocated to one of two conditions (one intervention and one control), with randomisation stratifying for gender, age and symptom severity. Participants will be randomly allocated to receive one of two conditions. All groups will complete symptom and activity questionnaires each week. The intervention group will follow the protocol previously approved by the MQ HREC (520221263243784): 1. TYD Group

The research design is a parallel group randomised controlled trial. Applicants will be randomly allocated to one of two conditions (one intervention and one control), with randomisation stratifying for gender, age and symptom severity. Participants will be randomly allocated to receive one of two conditions. All groups will complete symptom and activity questionnaires each week. The intervention group will follow the protocol previously approved by the MQ HREC (520221263243784): 1. TYD Group. a. During Phase 1 (2 weeks), Baseline Phase, participants will be instructed to continue to perform their usual activities. b. During Phase 2 (2 weeks), Restriction Phase, participants will be instructed to reduce the frequency they perform the actions listed on the TYD-15 item questionnaire (TYD-15) to 2 times each week. Example items include: "I kept a healthy daily routine"; "I went to bed and woke up at a regular time"; "I prepared and ate a healthy meal". c. During Phase 3 (5 weeks), Recovery Phase, participants will be instructed to resume the frequency they perform the actions that they restricted in Phase 2 to 5 times each week. Behaviour will be prompted using automated daily text messages, which were approved by the MQ (HREC 5201831843909) for an earlier study. Adherence throughout the phases will be monitored via the symptom and activity questionnaires administered each week.

Sponsors

Macquarie University
Lead SponsorUniversity

Study design

Allocation
Randomised controlled trial
Primary purpose
Treatment
Masking
Open (masking not used)

Eligibility

Sex/Gender
All
Age
18 Years to No maximum
Healthy volunteers
Yes

Inclusion criteria

(a) Australian resident; (b) Are aged 18 years or older.

Exclusion criteria

People who:. 1. Have moderate or higher levels of symptoms of anxiety or depression 2. Are not living in Australia 2. Are unable to read or understand English 3. Are currently receiving psychological treatment 4. At risk of suicide or self-harm

Outcome results

None listed

Source: ANZCTR · Data processed: May 22, 2026