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Prooxidant-antioxidant balance indicators, adrenal cortex and medullary hormones and growth factors in patients with salivary gland tumours

Prooxidant-antioxidant balance indicators, adrenal cortex and medullary hormones and growth factors pre and post surgery in patients with salivary gland tumours

Status
Completed
Phases
Unknown
Study type
Observational
Source
ANZCTR
Registry ID
ACTRN12624001482550
Enrollment
30
Registered
2024-12-18
Start date
2024-01-28
Completion date
2024-09-17
Last updated
2025-01-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

The main aim of the research project will be to evaluate indicators of prooxidant-antioxidant balance, adrenal cortex and medullary hormones, and growth factors in patients diagnosed and treated at the Department of Laryngology. Patients with a diagnosed tumor (benign or malignant) of the parotid glands after histopathological verification and computed tomography (CT) have been qualified for surgical treatment in the Department of Laryngology. Blood for biochemical tests will be collected twice, i.e. before surgery and after surgery (after 10 days). The research complements existing scientific information, among other valuable diagnostic information and guidance for postoperative management in patients after removal of benign or malignant tumors.

Interventions

The subject of the planned research is the evaluation of selected biochemical markers in blood in patients of the Department of Laryngology and Clinic of Laryngology of the Silesian Medical University in Katowice. Patients with diagnosed tumours (benign or malignant) of the parotid glands after prior histopathological verification and computed tomography (CT) were qualified for surgical treatment (superficial parotidectomy - complete removal of the superficial lobe of the parotid gland with pres

The subject of the planned research is the evaluation of selected biochemical markers in blood in patients of the Department of Laryngology and Clinic of Laryngology of the Silesian Medical University in Katowice. Patients with diagnosed tumours (benign or malignant) of the parotid glands after prior histopathological verification and computed tomography (CT) were qualified for surgical treatment (superficial parotidectomy - complete removal of the superficial lobe of the parotid gland with preservation of the facial nerve) in the Department of Laryngology. Blood for biochemical tests will be collected twice, i.e. before and after surgery (after 10 days). The material for testing (whole blood) will be provided by the Department of Laryngology to the Biochemistry Laboratory.

Sponsors

Medical University of Silesia, Katowice, Poland
Lead SponsorUniversity

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years
Healthy volunteers
No

Inclusion criteria

1.diagnosed tumor (benign or malignant) of the parotid gland after histopathological and computed tomography (CT) verification, 2. voluntary agreement to the examination, 3. at least 18 years of age

Exclusion criteria

1. lack of consent to participate in the study, 2. failure to be available on the scheduled day of surgery, 3. non-qualification for surgery (removal of benign and malignant tumors) 4. health contraindications to the procedure and collection of biological material.

Outcome results

None listed

Source: ANZCTR · Data processed: Feb 4, 2026