None listed
Conditions
Brief summary
The Phacoemulsification rate is on the rise, and post operative inflammation and infection is a devastating condition. Although Intracameral Moxifloxacin is effective in preventing the post operative endophthalmitis. The combination of dexamethasone and moxifloxacin intracameral offers a dual benefit. While moxifloxacin provides potent prophylaxis against infections, dexamethasone significantly reduces postoperative inflammation.
Interventions
After establishing the standard anesthesia, Phacoemulsification with foldable posterior chamber intraocular lens will be performed by a single Ophthalmic surgeon. At the end of surgery after securing a stable and formed Anterior Chamber (AC), intracameral injection of Dexamethasone Sodium Phosphate (Decadron, Searle) at 0.4mg/0.1ml mixed with 0.5mg/0.1ml in of 0.5% preservative free moxifloxacin (Vigamox, Alcon Laboratories) through 1cc syringe with viscoelastic cannula will be injected through
After establishing the standard anesthesia, Phacoemulsification with foldable posterior chamber intraocular lens will be performed by a single Ophthalmic surgeon. At the end of surgery after securing a stable and formed Anterior Chamber (AC), intracameral injection of Dexamethasone Sodium Phosphate (Decadron, Searle) at 0.4mg/0.1ml mixed with 0.5mg/0.1ml in of 0.5% preservative free moxifloxacin (Vigamox, Alcon Laboratories) through 1cc syringe with viscoelastic cannula will be injected through the side port, with in less than a minute. The eyelid retractor will be removed and 1 drop of (0.05ml of 5% same Moxifloxacin will be instilled in conjunctival cul-de- sac. After surgery ,the record of intervention will be secured with the ID of the patients in Hospital Management Information System(HMIS) for follow up on 1st ,10th and 40th post operative day.
Sponsors
Sihat Sahulat Card ,Lady Reading Hospital
Study design
Allocation
Randomised controlled trial
Intervention model
Parallel
Primary purpose
Prevention
Masking
Blinded (masking used)
Eligibility
Sex/Gender
All
Age
50 Years to No maximum
Healthy volunteers
No
Inclusion criteria
All those patients of both gender, ethnicities and geographical location ,with age related cataracts who have undergone Phacoemulsification with out any per operative complications and with posterior chamber intraocular lens will be included in this study.
Exclusion criteria
Patients with traumatic and complicated cataracts, previous intraocular surgeries will be excluded from the study. Those patients with history of steroid responsive glaucoma will also be excluded from the study.
Outcome results
None listed