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Evaluating the effect of amoxicillin dosage and timing of administration on postoperative complications after retained lower third molar extraction: A double-blind randomized controlled clinical trial

Evaluating the effect of amoxicillin dosage and timing of administration on postoperative complications after retained lower third molar extraction: A double-blind randomized controlled clinical trial

Status
Not yet recruiting
Phases
Phase 4
Study type
Interventional
Source
ANZCTR
Registry ID
ACTRN12624001414505
Enrollment
100
Registered
2024-11-29
Start date
2024-12-18
Completion date
2025-05-13
Last updated
2024-12-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

To study the antibacterial effect of amoxicillin 2 g 1 hour before surgery and amoxicillin 500 mg administered postoperatively versus amoxicillin 750 mg.

Interventions

Arm 1: Amoxicillin 2 g 1 hour before surgery. Arm 2: amoxicillin 500 mg administered postoperatively. Arm 3: Amoxicillin 750 mg administered postoperatively. Mode of administration Oral The tab is administer by the dentist

Sponsors

Universidad de Granada
Lead SponsorUniversity

Study design

Allocation
Randomised controlled trial
Primary purpose
Prevention

Eligibility

Sex/Gender
All
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

Retained third lower molars

Exclusion criteria

None

Outcome results

None listed

Source: ANZCTR · Data processed: Feb 4, 2026