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Does lower-leg hot-water immersion before or after exercise improve pain during and after exercise for people with osteoarthritis?

Does lower-leg hot-water immersion before or after exercise improve pain during and after exercise for people with osteoarthritis?

Status
Not yet recruiting
Phases
Unknown
Study type
Interventional
Source
ANZCTR
Registry ID
ACTRN12624001396516
Enrollment
20
Registered
2024-11-26
Start date
2024-12-02
Completion date
Unknown
Last updated
2024-12-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

This pilot study will be a 4x4 randomised, controlled cross-over design trial. Six participants with mild or moderate hip or knee osteoarthritis will be recruited from the community. Participants will complete 4 sessions: 1) 15-min pre-exercise lower leg immersion + 30-min exercise; 2) 30-min exercise + 15-min post-exercise lower leg immersion; 3) 15-min pre-exercise lower leg immersion + 30-min exercise + 15-min post-exercise lower leg immersion 4) 30-min exercise only (control). To quantify the intensity and duration of any analgesic effect, participants will rate their joint pain using the visual analogue pain scale; this will be recorded pre-exposure, every 5-10 min during exposure, immediately post-exposure, and then at regular intervals (at home via a pain diary) across 24 hours. Our hypothesis is that lower-leg hot-water immersion will reduce joint pain during and post-exercise, compared to the control condition.

Interventions

All participants will complete 3 water immersion (40ºC) sessions and a control session (in a randomised order): 1) 15-min pre-exercise lower leg immersion + 30-min exercise; 2) 30-min exercise + 15-min post-exercise lower leg immersion; 3) 15-min pre-exercise lower leg immersion + 30-min exercise + 15-min post-exercise lower leg immersion; 4) 30-min exercise only (control) There will be a 7-day washout between exposures. 1. 15-min pre-exercise lower leg immersion + 30-min exercise Location

All participants will complete 3 water immersion (40ºC) sessions and a control session (in a randomised order): 1) 15-min pre-exercise lower leg immersion + 30-min exercise; 2) 30-min exercise + 15-min post-exercise lower leg immersion; 3) 15-min pre-exercise lower leg immersion + 30-min exercise + 15-min post-exercise lower leg immersion; 4) 30-min exercise only (control) There will be a 7-day washout between exposures. 1. 15-min pre-exercise lower leg immersion + 30-min exercise Location: School of Physical Education, Sport and Exercise Sciences Aquatic Facility (University of Otago, Dunedin). Supervision: This session will be supervised by an American College of Sports Medicine (ACSM) registered clinical exercise physiologist (CEP), and the primary investigator (PI) or a research assistant; all supervising researchers are first aid trained. Attendance and session particulars (e.g., physiological indices etc.) will be recorded at each session by the supervising researcher. Exposure: Participants will complete a single 15-min hot water immersion session in 40 °C water followed by 30-min moderate intensity walk on a treadmill or cycle (intensity assessed via Borg RPE scale), followed by 15-min seated rest (no water immersion). Participants will be seated upright with water approximately below knee level. Duration: 60 min. 2. 30-min exercise + 15-min post-exercise lower leg immersion Location: School of Physical Education, Sport and Exercise Sciences Aquatic Facility (University of Otago, Dunedin). Supervision: This session will be supervised by an American College of Sports Medicine (ACSM) registered clinical exercise physiologist (CEP), and the primary investigator (PI) or a research assistant; all supervising researchers are first aid trained. Attendance and session particulars (e.g., physiological indices etc.) will be recorded at each session by the supervising researcher. Exposure: Participants will complete 15-min seated rest (no water immersion), followed by a single 30-min moderate intensity walk on a treadmill or cycle (intensity assessed via Borg RPE scale), followed by a single 15-min hot water immersion session in 40 °C water. Participants will be seated upright with water approximately below knee level. Duration: 60 min. 3. 15-min pre-exercise lower leg immersion + 30-min exercise + 15-min post-exercise lower leg immersion Location: School of Physical Education, Sport and Exercise Sciences Aquatic Facility (University of Otago, Dunedin). Supervision: This session will be supervised by an American College of Sports Medicine (ACSM) registered clinical exercise physiologist (CEP), and the primary investigator (PI) or a research assistant; all supervising researchers are first aid trained. Attendance and session particulars (e.g., physiological indices etc.) will be recorded at each session by the supervising researcher. Exposure: Participants will complete a single 15-min hot water immersion session in 40ºC water, followed by 30-min moderate intensity walk on a treadmill or cycle (intensity assessed via Borg RPE scale), followed by a single 15-min hot water immersion session in 40 °C water. Participants will be seated upright with water approximately below knee level. Duration: 60 min Adherence will be assessed via direct observation.

Sponsors

University of Otago
Lead SponsorUniversity

Study design

Allocation
Randomised controlled trial
Primary purpose
Treatment

Eligibility

Sex/Gender
All
Age
18 Years to 85 Years
Healthy volunteers
No

Inclusion criteria

- Has at least mild hip or knee osteoarthritis; - Fulfils the Physical Activity Readiness Questionnaire Plus questionnaire criteria, or participant's physician provides medical clearance for study participation; - Gives written consent; - Able to travel to the study centre to complete all sessions.

Exclusion criteria

- Not "passing" the Physical Activity Readiness Questionnaire Plus questionnaire, and physician refuses medical clearance for study participation; - Angina; - Recent myocardial infarction (< 3 months ago); - Implanted cardiac device (i.e. ICD, pacemaker etc.); - Heat intolerance; - Pregnancy; - Any other medical condition deemed a significant risk to study participation.

Outcome results

None listed

Source: ANZCTR · Data processed: Feb 4, 2026