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Children and Adolescents: Respiratory Infection and Long-term Effects (CARE Study)

A longitudinal study of post-viral sequelae following common respiratory infections in children and adolescents

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ANZCTR
Registry ID
ACTRN12624001361594
Acronym
CARE Study
Enrollment
1273
Registered
2024-11-13
Start date
2024-06-20
Completion date
2026-06-30
Last updated
2026-03-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

This study investigates ongoing symptoms following COVID-19 and influenza infections in children and teenagers. Parents of children who have had COVID-19 or influenza will be invited to participate. Initially, cases will be identified through presentations at the Women's and Children's Hospital and will then expand to include statewide notifications. After providing consent, participants (or their parents) will complete surveys at the start of the study and then again at 3, 6, and 12 months after the viral infection. These surveys will help researchers monitor any persistent health issues over time. The primary goal of the study is to understand how common these ongoing health problems are in young people and how they impact their daily lives.

Interventions

Children and adolescents aged 0 to 17 who have tested positive for COVID-19 or influenza are eligible for enrollment. Those who consent will be asked to complete a baseline, 3-month, 6-month, and 12-month online survey. Each online survey takes approximately 10 minutes. Participants are enrolled in the study for 12 months.

Sponsors

Women's and Children's Hospital Network
Lead SponsorGovernment body

Eligibility

Sex/Gender
All
Age
0 to 17 Years
Healthy volunteers
No

Inclusion criteria

Children and adolescents aged 0 to 17 who have tested SARS-CoV-2 positive (PCR or Rapid Antigen Tests) or influenza (PCR or Rapid Antigen Tests) in the previous 2 months are eligible for enrollment.

Exclusion criteria

1) Inability to give informed parental consent 2) No mobile phone number available 3) Children and adolescents who are under the care of the statewide WCHN Palliative care service

Outcome results

None listed

Source: ANZCTR · Data processed: Apr 4, 2026