None listed
Conditions
Brief summary
The primary purpose of this study is to compare the effects of home-based High-Intensity Interval Training (HIIT) with laboratory-based HIIT on the health of women with Polycystic Ovary Syndrome (PCOS) who are overweight or obese. The study will examine various health outcomes over a 12-week period, including cardiorespiratory fitness, body composition, and glycaemic control. The hypothesis is that home-based HIIT will be as effective as laboratory-based HIIT in improving these health outcomes. This study aims to provide a more accessible exercise option for women with PCOS, potentially offering a cost-effective and convenient way to manage their condition through home-based training. Participants will undergo baseline testing, engage in the HIIT program, and complete follow-up assessments to evaluate the long-term benefits post 12- week intervention. The study involves researchers from Victoria University, the University of Adelaide, and Monash University, ensuring a comprehensive approach to improving the quality of life for women with PCOS.
Interventions
This study will investigate the effects of 12 weeks of high-intensity interval training (HIIT) on females with polycystic ovary syndrome (PCOS). Participants will be randomly assigned to one of two groups: Home-Based HIIT (H-HIIT, intervention) and Laboratory-Based HIIT (L-HIIT, comparator). The H-HIIT intervention will involve three weekly sessions, with two sessions consisting of 12 x 1-minute intervals at 90-100% of maximum heart rate (HRmax) and one session of 8 x 4-minute intervals at 90-95
This study will investigate the effects of 12 weeks of high-intensity interval training (HIIT) on females with polycystic ovary syndrome (PCOS). Participants will be randomly assigned to one of two groups: Home-Based HIIT (H-HIIT, intervention) and Laboratory-Based HIIT (L-HIIT, comparator). The H-HIIT intervention will involve three weekly sessions, with two sessions consisting of 12 x 1-minute intervals at 90-100% of maximum heart rate (HRmax) and one session of 8 x 4-minute intervals at 90-95% HRmax, all followed by active recovery periods. These sessions will be conducted remotely via Zoom and will be supervised by an experienced member of the research team. Participants will be provided with a magnetic bike trainer to convert their regular bicycles into stationary bikes. Each session will include a warm-up, intervals, active recovery periods, and a cooldown period. A smartwatch with a heart rate sensor will be used to record and store data for each participant, with adherence tracked through session attendance and compliance assessed by exercise intensity data from the monitors.
Sponsors
Victoria University
Study design
Allocation
Randomised controlled trial
Intervention model
Parallel
Primary purpose
Treatment
Masking
Open (masking not used)
Eligibility
Sex/Gender
All
Age
18 Years to 45 Years
Healthy volunteers
No
Inclusion criteria
The inclusion criteria for the study require participants to be females aged between 18-45 years (pre-menopausal), diagnosed with Polycystic Ovary Syndrome (PCOS), insufficiently active (do not meet the minimum physical activity recommendations of 150 min of moderate to vigorous activity per week) and have a Body Mass Index (BMI) greater than 25 kg/m².
Exclusion criteria
The exclusion criteria include pregnancy or breastfeeding, smoking, diabetes, uncontrolled hypertension (greater than 160/100 mmHg), established cardiovascular disease (CVD), renal impairment, malignancy, or taking medications that interfere with the study endpoints (such as insulin sensitizers and anti-obesity drugs).
Outcome results
None listed