None listed
Conditions
Brief summary
Our objective is to evaluate the effect of a single dose of 2 g of oral amoxicillin administered 1 h before placement of single or multiple implants placed in a single surgical field in healthy adults versus placebo to reduce early failure of implants and postoperative infectious complications. The main hypothesis of this study is that there are no differences in the incidence of early implant failures and infectious complications after implant surgery oral implants in healthy, periodontally treated adults by administering a dose single dose of 2 grams of oral amoxicillin 1 hour before the intervention versus placebo.
Interventions
Our objective is to evaluate the effect of a single dose of 2 g of oral amoxicillin administered 1h before placement of single or multiple implants placed in a single surgical field in healthy adults versus placebo. Patient adherence is controlled by direct observation.
Sponsors
Master in Oral Surgery and Implantology, University of Granada
Study design
Allocation
Randomised controlled trial
Intervention model
Parallel
Primary purpose
Treatment
Masking
Blinded (masking used) (Subject, Caregiver, Investigator, Outcomes Assessor)
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
Patients 18 years and over • Subjects treated periodontally, if necessary, prior to placement of implants • Presence of sufficient bone and soft tissue that does not imply augmentation surgery in the moment of implant placement • Implants placed in a single surgical field
Exclusion criteria
Patients who, due to their medical condition, require antibiotic prophylaxis postoperative (risk of endocarditis) • Patients undergoing head and neck radiotherapy less than 2 years ago • Diabetics (controlled and uncontrolled) • Allergic to penicillin • Patients treated with antiresorptive drugs • Pregnant or breastfeeding • Immunocompromised • Patients who are taking antibiotics for other reasons • Implants that require simultaneous bone regeneration • Implants in which immediate loading is carried out • Immediate implants
Outcome results
None listed