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Stopping Haemorrhage by Application of Randomised Compression or Tourniquet (SHARC-TWO)

Comparison of inguinal fist compression versus commercial windlass tourniquet for reduction in femoral artery blood flow by untrained providers: a superiority, assessor-blinded, cross-over, randomised controlled trial

Status
Completed
Phases
Unknown
Study type
Interventional
Source
ANZCTR
Registry ID
ACTRN12624001054505
Acronym
SHARC-TWO
Enrollment
50
Registered
2024-08-30
Start date
2025-02-01
Completion date
2025-07-01
Last updated
2026-04-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

Effective haemorrhage control is crucial in cases of limb trauma involving arterial injury, such as shark attacks. International first aid guidelines recommend the use of arterial tourniquets as a primary treatment for life-threatening external bleeding. Manual pressure applied directly over a major artery proximal to the injury (Inguinal Fist Compression, IFC) is more accessible in a first-aid situation than commercial windlass tourniquets (CWTs). Stopping Haemorrhage by Application of Randomised Compression or Tourniquet (SHARC-Two) is a trial designed to examine which of these interventions is superior at reducing arterial blood loss when applied by a member of the general public. Based on a recent pilot study, we anticipate that IFC will achieve a greater reduction in femoral blood flow than a CWT when applied by untrained bystanders after brief infographic exposure.

Interventions

Inguinal Fist Compression (IFC) The provider will place the fist of their dominant hand at the midpoint of the recipient’s inguinal canal, midway between the anterior superior iliac spine and the pubic symphysis. The leg used (left or right) for each data collection session will be determined by the ergonomics of each testing space and will be recorded. Maximal pressure will then be applied over the compression point as per the technique reported by Taylor and Lamond for up to five minutes (see

Inguinal Fist Compression (IFC) The provider will place the fist of their dominant hand at the midpoint of the recipient’s inguinal canal, midway between the anterior superior iliac spine and the pubic symphysis. The leg used (left or right) for each data collection session will be determined by the ergonomics of each testing space and will be recorded. Maximal pressure will then be applied over the compression point as per the technique reported by Taylor and Lamond for up to five minutes (see below for complete description of this technique from the original paper). Commercially manufactured windlass tourniquet (CWT) The CWT used will be the Combat Application Tourniquet manufactured by C-A-T Resources. The provider will apply the CWT to the upper thigh of the recipient and the windlass rotated to and locked at the maximum tolerable tightness for the recipient. Application of the CWT will be over clothing as to emulate real world ultilsation for up to five minutes. Infographics Separate infographics were developed for the IFC and CWT which outline step-by-step instructions on the application of each intervention. The IFC infographic was adapted from the that used in the study conducted by Taylor and Lamond. The CWT infographic was adapted from the manufacturer’s instructions. Both infographics were tested in an initial pilot study and further developed with input from a consumer advisory group with members of the general population. Providers in this study will be exposed to these infographics immediately prior to application of each technique and also be available for reference during their application. Members of the research team will be supervising each episode of technique application but will not interfere or coach providers unless there is a concern for participant safety. There will be a 2-3 minute washout period between application by each provide during which the room will be reset and the sonographer will ensure return of normal blood flow to the leg. The protocol for inguinal compression from Taylor and Lamond (The SHARC study) was as follows: One member of the pair wearing shorts lay down supine on a mattress on the floor. The other volunteer in the pair then placed their fist at the compression point (midpoint of the inguinal canal, midway between the anterior superior iliac spine [ASIS] and pubic symphysis). Compression was then performed by the volunteer, by applying full bodyweight pressure through their fist over the compression point.

Sponsors

Gold Coast Hospital and Health Service
Lead SponsorHospital
Bond University
Lead SponsorUniversity

Study design

Allocation
Randomised controlled trial
Intervention model
Crossover
Primary purpose
Treatment
Masking
Blinded (masking used) (Investigator, Outcomes Assessor)

Eligibility

Sex/Gender
All
Age
18 Years to 59 Years
Healthy volunteers
Yes

Inclusion criteria

Aged between 18-59 years (inclusive) English language fluency (including as a second language) No formal medical training beyond first-aid No training in arterial tourniquet application

Exclusion criteria

For providers: Diagnosis, or evidence of, conditions that could potentially be exacerbated by participation as a provider: Musculoskeletal e.g., carpal tunnel syndrome, previous shoulder dislocation or surgery (e.g. reconstruction), recent injury For recipients: Diagnosis, or evidence of, conditions that could potentially be exacerbated by participation as a recipient Musculoskeletal e.g. previous groin surgery (e.g. hernia repair, hip replacement), recent injury Vascular e.g. arterial venous malformation or aneurysmal disease of the femoral artery; peripheral vascular disease, including PSV of the SFA outside the normal reference range Neurological e.g. peripheral nerve disease Haematological e.g.hypercoagulability, coagulopathy or anticoagulation Dermatological e.g. severe dermatitis, infection or sunburn

Outcome results

None listed

Source: ANZCTR · Data processed: May 1, 2026