None listed
Conditions
Brief summary
The sacroiliac (SI) joints, crucial for weight bearing and stabilized by robust ligaments, exhibit limited motion; their dysfunction, particularly noted in conditions leading to increased movement or fibrous adhesions, is linked to lower back pain. The diagnosis of SI joint dysfunction is one of exclusion, with specific physical tests helping in the confirmation of the diagnosis; however, therapeutic diagnostic injections can give definite confirmation, although it is a diagnostic test with variable reliability. Traditional treatments span NSAIDs and physical therapy all the way to corticosteroid injections and surgery. Recent studies focused the use of platelet-rich plasma (PRP) injections for sustaining pain relief and the restoration of joint function. Research on biologics, including PRP, is growing, with these treatments offering nondestructive alternatives that release growth factors from platelets for tissue repair and regeneration. The aim of the study is to report the efficacy of PRP in the treatment of sacroiliac joint dysfunction.
Interventions
This will be a comparative randomized controlled trial study,aim to compare the effectiveness of intra-articular corticosteroid injection with autologous platelet-rich plasma (PRP) injection among patients with sacroilitis. The patients will be divided into two groups that is Group A and Group B by lottery method. Group A will receive the Intraarticular Corticosteroid Injection and will be considered as control where as the Group B will receive the Autologus Platelet Rich Plasma Injection and wi
This will be a comparative randomized controlled trial study,aim to compare the effectiveness of intra-articular corticosteroid injection with autologous platelet-rich plasma (PRP) injection among patients with sacroilitis. The patients will be divided into two groups that is Group A and Group B by lottery method. Group A will receive the Intraarticular Corticosteroid Injection and will be considered as control where as the Group B will receive the Autologus Platelet Rich Plasma Injection and will be considered as Intervention group. Patient in each group will be given appointment for the day of procedure to be performed. Group B Patients will receive Intraarticular Platelet Rich Plasma Injection. Before procedure patient's Platelets count will be checked and other heamotology related conditions including bleeding disorders will be ruled out. On the day of procedure, patient's vitals will be checked. After that Nursing Assistant will preload the Collecting Syringe with 1 ml Acid Citrate Dextrose. After adopting aseptic technique including wearing gloves and skin cleansing with Pyodine, 15 ml blood will be collected from the patient. Blood will be placed in Centrifuge machine. 1st soft spin will be given and then the hard spin. The heamatologist will collect the lower level of plasma along with buffy coat. Patient's Painful Sacroiliac joint will again be identified. Ligocaine gel will applied for 5 minutes. The aseptic techniques including the drapping and skin cleansing will follow. Patient will receive the Platelet Rich Plasma in affected joint only. The procedure will be performed by Consultant Doctor Physical Medicine and Rehabilitation. Patient will be retained in the Hospital fro next 30 minutes. The whole procedure starting from Patients in Group B reporting to hospital till allowing to leave will take 90 minutes. Also all the processes will be performed under the supervision of researcher.
Sponsors
Combined Military Hospital Kohat
Study design
Allocation
Randomised controlled trial
Intervention model
Parallel
Primary purpose
Treatment
Masking
Blinded (masking used) (Subject)
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Healthy volunteers
No
Inclusion criteria
1. The diagnosis of sacroiliac joint dysfunction-related pain involved a combination of clinical assessments, imaging, and the exclusion of other potential pain sources alongside positive findings in at least three provocative tests, including Patrick’s test, compression test, distraction test, Gaenslen’s test, thigh thrust test, and pain upon applying pressure to the SI joint. 2. Age group from 18 to 70 years 3. Patients of both genders.
Exclusion criteria
1. Sacroiliac joint dysfunction can be related to inflammatory and septic conditions or linked with spinal deformities such as scoliosis and kyphosis. Additionally, other spinal pathologies are ruled out during diagnosis. 2. Overlying soft tissue infection. 3. Uncontrolled diabetes mellitus. 4. Coagulation disorders 5. Patients Using Warfarin and Heparin 6. Inflammatory/Septic Arthritis
Outcome results
None listed