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Stomach Electrical Activity Following Oesophageal Cancer Surgery

Measuring Gastric Conduit Electrophysiology at 12 months post Ivor-Lewis Oesophagectomy to Characterise Delayed Gastric Conduit Emptying after Oesophageal Cancer Surgery

Status
Not yet recruiting
Phases
Unknown
Study type
Interventional
Source
ANZCTR
Registry ID
ACTRN12624000822583
Enrollment
40
Registered
2024-07-04
Start date
2024-07-31
Completion date
2026-07-30
Last updated
2024-07-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

This study investigates the characteristic electrical activity of the stomach conduit in patients with delayed gastric conduit emptying (DGCE), a clinical condition characterised by persistent nausea and difficulty swallowing after oesophageal cancer surgery. Who is it for? You may be eligible for this study if you are an adult male or female who has previous has had oesophageal cancer surgery at Peter MacCallum Cancer Centre atleast 12 months ago. Study details All participants will undergo a series of patient questionnaires regarding their symptoms, followed by a 4-hour gastric motility assessment using the device known as 'Gastric Alimetry', which works similarly to an ECG for the stomach. This will facilitate the identification of electrical activity characteristics for DGCE and validate the role of Alimetry in diagnosing DGCE.

Interventions

Gastric Alimetry is a non-invasive transcutaneous device which has been validated in assessing gastric motility in patients, using cutaneous sensors to monitor gastric electrophysiology and comparing to patient reported symptoms using patient feedback tools. The technology uses a high-resolution array of 64 electrodes applied to the anterior abdominal wall and epigastrium with the intention of measuring gastric electrical activity. It is comparable to an ECG test of the heart, however longer in

Gastric Alimetry is a non-invasive transcutaneous device which has been validated in assessing gastric motility in patients, using cutaneous sensors to monitor gastric electrophysiology and comparing to patient reported symptoms using patient feedback tools. The technology uses a high-resolution array of 64 electrodes applied to the anterior abdominal wall and epigastrium with the intention of measuring gastric electrical activity. It is comparable to an ECG test of the heart, however longer in duration to account for the lower frequency of the gastric electrical activity. Its non-invasive component provides an acceptable alternative to other measurement tools for gastric electrical activity, however the clinical utility in patients post-oesophagectomy is not yet explored. Patients will only be assessed with Gastric Alimetry as part of their enrollment in the study. Information that will be assessed from participants includes information from electronic medical records, study-specific questionnaires, as well as gastric motility activity. The patient questionnaire is anticipated to take 20 minutes to complete, and the gastric motility assessment is anticipated to take approximately 4 hours. The administration of the gastric motility assessment will be undertaken by a trained medical doctor. Adherence to the gastric motility assessment is binary and measured by whether the participant is able to complete the entire duration of the assessment as well as all study questionnaires.

Sponsors

A/Prof Cuong Duong
Lead SponsorIndividual

Study design

Allocation
Non-randomised trial
Intervention model
Parallel
Primary purpose
Diagnosis
Masking
Open (masking not used)

Eligibility

Sex/Gender
All
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

- Patients least 12 months post oesophagectomy at Peter MacCallum Cancer Centre - Adults aged 18 and over

Exclusion criteria

None

Outcome results

None listed

Source: ANZCTR · Data processed: Feb 4, 2026