None listed
Conditions
Brief summary
This observational study aims to assess whether a residual heparin effect is contributing to post-operative bleeding in cardiac surgical patients at a single institution. It will also assess whether testing for a residual heparin effect will help in reduce the transfusion of blood components perioperatively. The hypothesis being tested is that a proportion of patients undergoing cardiac surgery are returning to ICU with heparin activity affecting their normal coagulation and that this might result in inappropriate administration of platelets and other blood components.
Interventions
Observational study of adult patients undergoing cardiac surgery. A single blood sample will be drawn from existing arterial cannulae and thromboelastography will be performed at 2-hours following return to ICU to assess for a residual heparin effect. The primary outcome will be to assess for a difference in bleeding, defined by drain tube outputs up to 24 hours post-operatively, identified between patients who do and do not have a residual heparin effect detected. Observational data will be col
Observational study of adult patients undergoing cardiac surgery. A single blood sample will be drawn from existing arterial cannulae and thromboelastography will be performed at 2-hours following return to ICU to assess for a residual heparin effect. The primary outcome will be to assess for a difference in bleeding, defined by drain tube outputs up to 24 hours post-operatively, identified between patients who do and do not have a residual heparin effect detected. Observational data will be collected from arrival in ICU until ICU discharge and will follow routine monitoring of post-cardiac surgical patients. There will be no further participant follow-up.
Sponsors
Liam O'Bryan - St Vincent's Hospital Melbourne
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
Adult patients undergoing any elective or emergency cardiac surgery
Exclusion criteria
All cardiac surgical patients eligible
Outcome results
None listed