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Omega-3 indices following chia and flax seed comsumption in populations following a low fat, wholefood, plant-based dietary pattern

Omega-3 indices in healthy adult populations following low fat, wholefood, plant-based dietary patterns following consumption of chia and flax seeds high in alpha-linolenic acid.

Status
Not yet recruiting
Phases
Unknown
Study type
Interventional
Source
ANZCTR
Registry ID
ACTRN12624000711516
Enrollment
42
Registered
2024-06-07
Start date
2024-06-17
Completion date
2024-08-05
Last updated
2024-06-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

This intervention study is designed to assess and quantify the effect of flax and chia seeds, which are high in alpha-linolenic acid (ALA) which can theoretically be converted into the long chain omega 3 fatty acids eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA). The population will be those habitually following a low fat, whole food plant-based diet. This population has been selected as they have a low total, and omega-6 fat intake, which can compete with ALA for conversion to DHA and EPA. The proposed study will consist of a randomised controlled intervention for 8 weeks in a population following a low fat (<20% of total energy intake) whole food plant-based diet including: 1) Flax and chia seeds (22.5 grams of flax seeds and 22.5 grams of chia seeds containing ~10.25 grams of ALA + habitual low fat whole food plant-based diet Or 2) Continued habitual low fat whole food plant-based diet. It is hypothesied that the chia/flax intervention will not induce a significant difference in omega-3 indices

Interventions

Flax and chia seeds (22.5 grams of flax seeds and 22.5 grams of chia seeds containing ~10.25 grams of ALA) in a population following a whole food plant-based diet. The flax and chia seeds will be incorporated daily (45g/day) into participants existing diets by mixing or adding to meals i.e. sprinkled on oats for 8 weeks. Adherence will be monitored by asking participants to return all seeds which were not consumed during the 8 week intervention. Both groups will be asked to continue eating th

Flax and chia seeds (22.5 grams of flax seeds and 22.5 grams of chia seeds containing ~10.25 grams of ALA) in a population following a whole food plant-based diet. The flax and chia seeds will be incorporated daily (45g/day) into participants existing diets by mixing or adding to meals i.e. sprinkled on oats for 8 weeks. Adherence will be monitored by asking participants to return all seeds which were not consumed during the 8 week intervention. Both groups will be asked to continue eating their existing low fat (<20%) whole food plant-based diets. Additionally, both groups will also complete a validated online 24 hour diet recall to measure adherence to the intervention.

Sponsors

University of Wollongong
Lead SponsorUniversity

Study design

Allocation
Randomised controlled trial
Intervention model
Parallel
Primary purpose
Prevention
Masking
Blinded (masking used) (Outcomes Assessor)

Eligibility

Sex/Gender
All
Age
18 Years to No maximum
Healthy volunteers
Yes

Inclusion criteria

• 18-years-old or older • Habitual dietary intake of a whole food, plant-based (WFPB) low fat (<20%) diet > 6 months (Validated with a food frequency questionnaire (FFQ))

Exclusion criteria

• Moderate or high fat diet ( greater than 20% of total energy intake) • Dairy or meat intake • Currently consuming or consumed omega-3 supplements including algal supplements in past 3 months. * Greater than 10 grams of chia, flax, or hemp seeds consumed daily • Flaxseed or chia seed allergy

Outcome results

None listed

Source: ANZCTR · Data processed: Feb 4, 2026