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Effects of resistance training on pain, well-being, and inflammation in chronic low back pain

Effects of resistance training on pain, well-being, and inflammation in chronic low back pain

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ANZCTR
Registry ID
ACTRN12624000624583
Enrollment
1
Registered
2024-05-14
Start date
2024-07-24
Completion date
2024-12-31
Last updated
2024-09-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

A 12-week parallel-group randomised controlled trial examining the effects of a supervised resistance training on pain intensity, well-being, and inflammation compared to usual care in adults with chronic non-specific low back pain will be conducted. It is hypothesised that 12 weeks of resistance training will improve pain intensity, well-being and inflammation compared to usual care in adults with chronic non-specific low back pain.

Interventions

Participants will complete a 12-week supervised resistance training program. Across this time, they will attend two group-based (3-4 participants) 60-minute face-to-face resistance training sessions per week (24 total sessions), prescribed and supervised by a qualified physiotherapist from the research group. Before the start of the intervention, a physical assessment (health history; lower back assessment and blood pressure) will be conducted by the physiotherapist. Resistance training sessions

Participants will complete a 12-week supervised resistance training program. Across this time, they will attend two group-based (3-4 participants) 60-minute face-to-face resistance training sessions per week (24 total sessions), prescribed and supervised by a qualified physiotherapist from the research group. Before the start of the intervention, a physical assessment (health history; lower back assessment and blood pressure) will be conducted by the physiotherapist. Resistance training sessions will be individualised based on the participant’s muscle strength. After learning the correct technique of each exercise, muscle strength will be determined by a series of submaximal strength tests in week three to determine the required training intensity. Resistance training sessions will consist of a ten-minute general warm up, including dynamic exercises for the trunk, legs, and shoulders. After warm-up, participants will perform 3 sets and 8-12 repetitions of the following resistance exercises with a barbell and weights: squat (1), barbell row (2), deadlift (3), and bench press (4). The selection of exercises is based on a prior study with a similar population and was considered safe. The training intensity will initially be 50% of the maximal strength (adaptation phase) and will gradually increase by 10% every 3 weeks, which is informed by previous studies. Adherence to the resistance training sessions will be assessed by documenting the overall training session attendance, within-session training load completed and rate of perceived exertion (RPE) for each training session.

Sponsors

Deakin University
Lead SponsorUniversity

Study design

Allocation
Randomised controlled trial
Intervention model
Parallel
Primary purpose
Treatment
Masking
Blinded (masking used) (Investigator, Outcomes Assessor)

Eligibility

Sex/Gender
All
Age
18 Years to 55 Years
Healthy volunteers
No

Inclusion criteria

(a) adult (aged 18-55 years), (b) has non-specific (no known specific pathology) chronic (12 weeks or longer) low back pain (pain located between the costal margin and above the inferior gluteal folds, with or without leg pain).

Exclusion criteria

(a) history of spinal surgery, spine trauma (e.g. fracture or car accident), cauda equina symptoms, known structural scoliosis, symptomatic radiculopathy, inflammatory spondyloarthropathies, or non-musculoskeletal causes of low back pain (LBP) (e.g. infection), (b) inability to communicate in English, (c) pregnancy, lactating or <1 year postnatal, (d) any absolute contraindication for exercise training, (e) participation in resistance training or sport that involves resistance training in the last three months (>1 session per month), (f) experienced an injury in the last six weeks.

Outcome results

None listed

Source: ANZCTR · Data processed: Feb 4, 2026