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A study to compare between 2 pain relief blocks after total knee arthroplasty surgery.

Impact of adductor canal block versus femoral nerve block for post-operative analgesia in total knee arthroplasty.

Status
Completed
Phases
Unknown
Study type
Interventional
Source
ANZCTR
Registry ID
ACTRN12624000616572
Enrollment
60
Registered
2024-05-13
Start date
2022-01-01
Completion date
2022-12-30
Last updated
2024-05-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

1. The purpose of the study is to compare analgesic effect of Adductor canal block ( ACB ) and femoral nerve block ( FNB ) in patients undergoing Total Knee Arthroplasty. 2. The block will be done with 20mls of 0.25% Bupivacaine in femoral nerve block and adductor canal block. 3.Hypothesis: Adductor canal block offers similar pain relief in comparison to femoral nerve block with less motor weakness aiding early mobilization.

Interventions

Patients are randomly assigned to receive either adductor canal block (group A, interventional) or femoral nerve block (group B, comparator) after total knee arthroplasty as a part of post operative analgesia. An ultrasound guided single shot adductor canal block will be done after the surgery is completed and sterile dressing is applied. The block in this group will be done with 20 mls of 0.25% Bupivacaine. One dedicated consultant anaesthetist will be assigned to this group to perform the bloc

Patients are randomly assigned to receive either adductor canal block (group A, interventional) or femoral nerve block (group B, comparator) after total knee arthroplasty as a part of post operative analgesia. An ultrasound guided single shot adductor canal block will be done after the surgery is completed and sterile dressing is applied. The block in this group will be done with 20 mls of 0.25% Bupivacaine. One dedicated consultant anaesthetist will be assigned to this group to perform the block to avoid inter individual block performance bias. A pain nurse followed up the patient in recovery and in ward and collected patient data, who was blinded to the study group to which the patient is assigned. Patient Control Analgesia was prescribed for all patients with morphine and it will be prepared as an intravenous infusion with morphine 30mg taken in 12 ml Normal Saline, diluted to 2 mg/ml concentration. Analgesia will be self administered by patient using a automatic pump with each bolus dose administered delivering 1 mg per bolus dose with 5 minutes lockout interval and 30 mg maximum dose in 4 hours for 24 hours. Patient will receive multimodal analgesia for pain control after the surgery with paracetamol 1 g four times a day. Both groups will receive same protocol to avoid bias. Early mobilisation and patient satisfaction data were collected.

Sponsors

King Hamad University Hospital
Lead SponsorHospital

Study design

Allocation
Randomised controlled trial
Intervention model
Parallel
Primary purpose
Treatment
Masking
Blinded (masking used) (Outcomes Assessor)

Eligibility

Sex/Gender
All
Age
40 Years to 80 Years
Healthy volunteers
No

Inclusion criteria

1. Patients undergoing primary Total Knee Arthroplasty (TKA), 2. Age 40–80 years of either sex, 3. The American Society of Anesthesiologists (ASA) Physical status classes I and II.

Exclusion criteria

1. ASA physical status classes > III, 2. History of allergy/contraindications to morphine, local anaesthetics, nonsteroidal anti-inflammatory drugs, paracetamol, central neuraxial block and peripheral nerve blocks 3. Patients who are receiving regular opioids. 4. Patients planned for complex TKA or revision TKAs. 5. Patient refusing consent.

Outcome results

None listed

Source: ANZCTR · Data processed: Feb 4, 2026