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The Effects of Anesthetizing the Lower Waist with an Injection in the Waist on the Waves in the Heart Strip in Pregnant Women Who Are Planned for Non-Urgent Caesarean Section or Overdue

Comparison of the Effects of spinal anesthesia on Frontal QRS-T angle in term and postterm pregnancies planned for elective cesarean section: a prospective study

Status
Completed
Phases
Unknown
Study type
Observational
Source
ANZCTR
Registry ID
ACTRN12624000596505
Enrollment
120
Registered
2024-05-09
Start date
2024-06-03
Completion date
2024-12-23
Last updated
2025-09-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

Spinal anesthesia is a frequently used method in cesarean section operations. Spinal anesthesia applications can also cause these rhythm disorders. With our study, we aimed to investigate the effects of spinal anesthesia on the frontal QRS-T angle in term and postterm pregnant women who are planned for elective Caesarean section.

Interventions

SUMMARY OF THE METHOD Patients will be divided into two groups of 60 based on gestational age. Group A (those who are at 42 weeks of gestation and above) Group B (those who are less than 42 weeks of gestation) After obtaining informed consent from the patients, venous access will be established with an 18 G peripheral vein cannula and standard monitoring (ECG, SpO2, NIBP) will be applied to the patients who will be taken to the operation room. Basal systolic arterial pressure (SAP) and heart rat

SUMMARY OF THE METHOD Patients will be divided into two groups of 60 based on gestational age. Group A (those who are at 42 weeks of gestation and above) Group B (those who are less than 42 weeks of gestation) After obtaining informed consent from the patients, venous access will be established with an 18 G peripheral vein cannula and standard monitoring (ECG, SpO2, NIBP) will be applied to the patients who will be taken to the operation room. Basal systolic arterial pressure (SAP) and heart rate (HR) will be recorded. The first ECG will be done in the operating room before the procedures are performed by surgical nurse. Both groups will receive volume replacement with 10 ml/kg 0.9% isotonic NaCl for 30 minutes before anesthesia. The second ECG recording will be performed. The patients will be placed in a sitting position and the puncture site will be disinfected with 10% povidone-iodine antiseptic solution. After sterile draping, 2.5 ml hyperbaric bupivacaine will be administered by reaching the subarachnoid space with a 25 G Quincke spinal needle from the L3-L4 or L4-L5 space administered by registered anaesthesist. Following the application, patients will be placed on their back. In all cases, a 12-lead ECG recording will be taken while resting in the supine position after resting for at least 10 minutes, with a paper speed of 25 mm per second, a height of 10 mm/Mv and a filter range of 0.16-100 Hz. In ECG evaluation, QT and Tp-e interval measurements will be calculated with the help of magnifying glasses. ECGs will be measured before the operation (T1), after spinal anesthesia (T2), at the 5th minute after spinal anesthesia (T3), at the 10th minute after spinal anesthesia (T4) and at the 30th minute after spinal anesthesia (T5).

Sponsors

Ahmet Kaya
Lead SponsorIndividual

Eligibility

Sex/Gender
All
Age
18 Years to 45 Years
Healthy volunteers
No

Inclusion criteria

120 patients aged between 18 and 45 who will undergo elective cesarean section with ASA II will be included in the study.

Exclusion criteria

Patients with contraindications for neuraxial anesthesia, injection site infection, severe hypovolemia, increased intracranial pressure, coagulopathy or bleeding diathesis, known local anesthetic allergy, severe mitral and/or aortic stenosis, abnormal serum electrolyte levels, heart rate-corrected QT (QTc). duration > 440 ms, drug abuse affecting QTc interval duration, family history of long QT syndrome, unstable angina pectoris, chronic obstructive pulmonary disease, ejection fraction <40%, severe heart failure, severe atrioventricular block, an arrhythmia disorder other than coronary sinus rhythm , liver and kidney disease, anemia, muscle-nerve disease and obesity were excluded from the study. Additionally, patients who underwent permanent battery placement and refused to participate in the study will also be excluded.

Outcome results

None listed

Source: ANZCTR · Data processed: Feb 4, 2026