None listed
Conditions
Brief summary
This Study aims to understand the best way to offer Australian Aboriginal and Torres Strait Islander Peoples lung cancer screening. Who is it for? You may be eligible to join this study if you are an Aboriginal or Terres Strait Islander person aged between 50 to 80 years old, and at high risk for developing lung cancer. Study details. All participants who complete an eligibility questionnaire and are found to be at high risk of developing lung cancer will be offered a low dose CT chest scan. Participants will be invited to complete a Lung Health Questionnaire, a Quality-of-Life questionnaire on enrolment then an annual health assessment questionnaire for up 10 years. Participants who do not meet the eligibility criteria for a low dose CT chest scan will be invited to participate in the Annual Health Assessment by agreeing to complete a questionnaire every year for up to 10 years. It is hoped that this research project will contribute to lung cancer screening research to detect lung cancer so it can be treated early.
Interventions
Low dose CT chest scan screening for people at high risk of lung cancer who meet screening eligibility criteria
A low dose CT scan which usually has a radiation dose of about 1.5mSv will be provided by registered Medical Imaging Providers by their Radiographers and Radiologists in accordance to their Standard Operating Procedures. The dose of radiation will be monitored for each scan. The scan does not involve contrast and may take 10-15 minutes to complete..
Sponsors
The University of Queensland
Study design
Allocation
Non-randomised trial
Intervention model
Single group
Primary purpose
Prevention
Masking
Open (masking not used)
Eligibility
Sex/Gender
All
Age
50 Years to 80 Years
Healthy volunteers
No
Inclusion criteria
Aboriginal and Torres Strait Islander people who are generally fit and well Aboriginal and Torres Strait Islander people aged 50 to 80 years who have a 20 pack-year smoking history and currently smoke or quit within the past 15 years (2021 US Preventative Services Task Force (USPSTF) criteria). Aboriginal and Torres Strait Islander people aged 50 to 70 years who have a history of cigarette smoking of at least 30 pack years, and, if former smokers, quit within the previous 10 years (Medical Services Advisory Committee (MSAC) criteria). Aboriginal and Torres Strait Islander people assessed as having a PLCOm2012 lung cancer risk score assessment of more than 1.5 percent over 6 years.
Exclusion criteria
Clinical symptoms suspicious for lung cancer e.g., haemoptysis, chest pain, weight loss. Any medical condition, such as severe heart disease (e.g., unstable angina, chronic congestive heart failure), acute or chronic respiratory failure, home oxygen therapy, bleeding disorder, that in the opinion of the investigator could jeopardize the subject’s safety during participation in the study or unlikely to benefit from screening due to shortened life-expectancy from the co-morbidities. Have been previously diagnosed with lung cancer. Have had other non-curatively treated cancer outside the lung. Pregnancy Pneumonia or bronchitis requiring antibiotic treatment within the last 12 weeks. Unwilling to have a spiral chest CT. Chest CT within 2 years Does not fit into CT scanner table. Cannot lie on CT scanning table on the back with arms over the head. Received chemotherapy or cytotoxic drugs within the last 6 months. Unwilling to sign a consent.
Outcome results
None listed