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Efficacy of a school-based air filtration project on indoor air quality and children's health

Efficacy of a school-based air filtration project on indoor air quality and children's health : a cluster randomized, double-blind, crossover trial

Status
Not yet recruiting
Phases
Unknown
Study type
Interventional
Source
ANZCTR
Registry ID
ACTRN12624000484549
Enrollment
50
Registered
2024-04-19
Start date
2025-04-23
Completion date
2025-08-01
Last updated
2025-09-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

This study is a cluster randomized, double-blind, crossover trial to develop a school-based HEPA filter intervention program targeting school children aged 6-13 years in Melbourne, Australia, and evaluate its effectiveness to improve school indoor air quality and children’s health. We hypothesized that the intervention would improve school indoor air quality and children's health. The study will fill information gaps for the indoor air quality regulatory framework, providing guidelines and recommendations that support health promotion and disease prevention for children in schools.

Interventions

Active (intervention group) high-efficiency particulate air (HEPA) filters will be conducted in the classrooms in Primary schools from Monday to Friday for three months. We will choose the Air filter: Aeris 3-IN-1 Pro Air Purifier(Aeris Cleantec, AG, Switzerland). The AERIS 3-IN-1 Pro Air Purifier has 3 layers of filters: pre-filter for large particles, activated carbon deodorization filter for gas and odours, and HEPA filtration with ultra-fine dust filter for ultra-fine dust. Air filters will

Active (intervention group) high-efficiency particulate air (HEPA) filters will be conducted in the classrooms in Primary schools from Monday to Friday for three months. We will choose the Air filter: Aeris 3-IN-1 Pro Air Purifier(Aeris Cleantec, AG, Switzerland). The AERIS 3-IN-1 Pro Air Purifier has 3 layers of filters: pre-filter for large particles, activated carbon deodorization filter for gas and odours, and HEPA filtration with ultra-fine dust filter for ultra-fine dust. Air filters will be checked for functionality by professional personnel before deploying in a school. Researchers will install air filters in the appropriate place in the classroom. During the implementation of the intervention, project staff will be required to switch on and off the air filters, check the quality, and fill in the air filter usage log every day. All purifiers should be switched on 1 h before schoolchildren enter the classroom and switched off after the schoolchildren leave the room. The intervention will be starting at 7:30 and ending at 15:30 from Monday to Friday according to the school schedule. Regular weekly field observations will be made. A research assistant will assess the air filters at the school visits to document functionality and whether the air filters are on at the time of the school visit. If the air filters do not work properly, the research assistant will contact professional personnel repair it. If the air filters are not in correct position, the research assistant will communicate with the school contacts to encourage compliance.

Sponsors

Yuming Guo
Lead SponsorIndividual

Study design

Allocation
Randomised controlled trial
Intervention model
Crossover
Primary purpose
Educational / counselling / training
Masking
Blinded (masking used) (Subject, Caregiver, Investigator, Outcomes Assessor)

Eligibility

Sex/Gender
All
Age
6 Years to 13 Years
Healthy volunteers
Yes

Inclusion criteria

(1) Students aged 6-13 years in the selected classes. (2) Have no plans to change schools or households within the upcoming 3 months. (3) Students and their caregivers are able to understand and provide informed consent.

Exclusion criteria

(1) Lung disease, other than asthma, that requires daily medication. (2) Inability to do lung function testing. (3) Current and diagnosed cardiovascular disease, hepatitis, nephritis, mental illness, or other major diseases. (4) Decorated or plan to decorate home within three months.

Outcome results

None listed

Source: ANZCTR · Data processed: Feb 4, 2026