None listed
Conditions
Brief summary
The specific aims of this prospective observational study are: To investigate the short-term effects of ACTs on ventilation distribution and end-expiratory lung volume in adults with bronchiectasis. To examine the feasibility of EIT to assess the short-term effects of ACTs in adults with bronchiectasis in hospital outpatient clinic settings. To examine the feasibility of EIT to provide clinically meaningful outcomes of ACTs in adults with bronchiectasis. The objectives of this quantitative study are: To document and analyse the changes in ventilation distribution during ACTs in adults with bronchiectasis using EIT. To document the participant’s feedback on the experience of performing airway clearance with continuous EIT measurement. To document the clinician’s experience of using EIT as an outcome measure for ACTs in clinical settings. Study design: prospective observational cohort study using quantitative approaches.
Interventions
Electrical impedance tomography (EIT) monitoring during airway clearance techniques for those participants included in the study.
An electrode belt connected to EIT machine will be placed on the participant’s chest, the belt is worn at nipple level for males and below the breast tissues for females (between 4th and 6th intercostal space). EIT belt positioning is marked on the skin with a marker to ensure its fixed displacement during the measurement period.
Baseline measures of oxygen saturati
Electrical impedance tomography (EIT) monitoring during airway clearance techniques for those participants included in the study. An electrode belt connected to EIT machine will be placed on the participant’s chest, the belt is worn at nipple level for males and below the breast tissues for females (between 4th and 6th intercostal space). EIT belt positioning is marked on the skin with a marker to ensure its fixed displacement during the measurement period. Baseline measures of oxygen saturation will be recorded via pulse oximeter. EIT measurements will commence 5 minutes before ACTs and continue for the duration of the session. Participants will then perform their routine ACTs for up to 20mins (participants either complete their routine ACTs within 20mins or are requested to stop at 20mins). The ACTs performed were previously prescribed by their treating physiotherapist and are individualised. Airway clearance may involve breathing exercises, positive expiratory pressure (PEP) or oscillatory PEP devices, or a combination of inhaled therapy with devices. Details of ACTs performed by each participant will be collected. Sputum expectorated during and immediately after the ACTs are collected and measured. Oxygen saturation will be recorded again immediately after the ACTs. EIT measurements will cease 5 minutes after ACTs. After the measurements, participants complete a questionnaire regarding their ACTs experiences and rate whether the EIT measurements affected their ACTs.
Sponsors
Mater Health Brisbane
Study design
Allocation
Non-randomised trial
Intervention model
Single group
Primary purpose
Educational / counselling / training
Masking
Open (masking not used)
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
Study participants will be recruited from patients attending the Adult Bronchiectasis Clinic at Mater Hospital Brisbane. Has a diagnosis of bronchiectasis • Productive of secretions that require routine airway clearance • Performs ACTs regularly at home • Willing and able to provide informed consent
Exclusion criteria
• Contraindicated for ACTs, including chest trauma, facial trauma or facial burns, bleeding disorder, uncontrolled bronchospasm, and current haemoptysis. • Contraindicated for EIT measurements, including pacemaker, automatic implantable cardioverter defibrillator, and implantable pumps. • Inability to follow instructions. • Patients less than 18 years of age.
Outcome results
None listed