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Intravesical Microdox instillation versus standard practice for prevention of postoperative urinary tract infections: A Randomised Controlled Trial.

Intravesical Microdox instillation versus standard practice for prevention of postoperative urinary tract infections: A Randomised Controlled Trial.

Status
Not yet recruiting
Phases
Unknown
Study type
Interventional
Source
ANZCTR
Registry ID
ACTRN12624000429550
Enrollment
190
Registered
2024-04-09
Start date
2024-04-14
Completion date
Unknown
Last updated
2024-04-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

Urinary tract infections (UTIs) are the most common postoperative complication following pelvic organ prolapse surgery. The risk of UTI after incontinence and prolapse surgery has been reported to be 24-33%. This study will see if placing a small amount (50ml) of an antibacterial solution called Microdox when the urinary catheter is removed could decrease the risk of urinary tract infection after surgery. We are comparing this to our current practice, which is to remove the catheter without placing any liquid inside the bladder.

Interventions

50ml intravesical Microdox bladder instillation by a doctor immediately prior to removal of the urinary catheter and voiding trial following pelvic organ prolapse or continence surgery. The Microdox will be emptied as the patient voids and we will record the time to first void.

Sponsors

Mercy Womens Hospital
Lead SponsorHospital

Study design

Allocation
Randomised controlled trial
Primary purpose
Prevention

Eligibility

Sex/Gender
All
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

*Women aged 18 and over. *Able to give informed consent for participation in the trial * Women who have underwent pelvic organ prolapse or continence surgery

Exclusion criteria

• Permanent IDC • Other permanent indwelling urinary tract foreign body (e.g. ureteric stents, nephrostomy tube) or anatomical variant causing obstruction or recurrent infection (e.g. Untreated bladder stones or upper tract stones). • Age < 18 years

Outcome results

None listed

Source: ANZCTR · Data processed: Feb 4, 2026