None listed
Conditions
Brief summary
The current study will investigate the effect of meal time alteration on the quality of sleep, separately in early birds, night owls, and intermediate chronotypes. We hypothesize that taking the evening meal closer to bedtime reduces sleep quality in morning people, but not in night owls.
Interventions
10 early chronotype, 10 intermediate and 10 evening type participants will be randomly enrolled in this cross-over trial. Each participant’s usual sleep time would be determined by actigraphy and the instructions about timing of their meals (the time interval between meal consumption and sleep) would be based on their personal usual sleep time.
Arm 1 (control group):
Participants of the early meal group will be instructed to have their dinner 4 hours prior to going to bed,
Arm 2 (intervention)
10 early chronotype, 10 intermediate and 10 evening type participants will be randomly enrolled in this cross-over trial. Each participant’s usual sleep time would be determined by actigraphy and the instructions about timing of their meals (the time interval between meal consumption and sleep) would be based on their personal usual sleep time. Arm 1 (control group): Participants of the early meal group will be instructed to have their dinner 4 hours prior to going to bed, Arm 2 (intervention): Participants of the late meal group will take their dinner 1 hour prior to sleep. The intervention will go on for 3 consecutive days, followed by 11 days of washout. participants will continue their usual timing of other meals taken throughout the day and physical activity. There would be no instructions regarding the content of the meals and participants can choose their own meals. Compliance will be monitored throughout the study by submission of food and sleep diary on RedCap throughout the trial. Participants will wear an actigraph watch and will be asked to record their sleep and dietary intake during the intervention and washout period.
Sponsors
The University of Sydney
Study design
Allocation
Randomised controlled trial
Intervention model
Crossover
Primary purpose
Prevention
Masking
Blinded (masking used) (Investigator, Outcomes Assessor)
Eligibility
Sex/Gender
All
Age
18 Years to 45 Years
Healthy volunteers
Yes
Inclusion criteria
Understand English Adults 18-45 years old (older ages could affect the gut microbiota) Healthy (no acute or chronic disorders)
Exclusion criteria
Shift working Diagnosed sleep disorders such as insomnia, sleep apnea, etc. Taking medication affecting sleep including melatonin, Zolpidem, Lorazepam, antidepressants, etc. Pregnancy or lactating for women Yoyo dieting and changing their usual diet during the past month having observed blood in their stool during the past month Use of antibiotics during the past 3 months Metformin consumption during the past 3 months Having travelled across time zones during the past month *Not turning up for any of the 3 time-point assessments will be considered a drop out.
Outcome results
None listed