None listed
Conditions
Brief summary
This project builds on a previous double-blinded interventional study by our research team which aimed to investigate the impact of a hydrolysed collagen supplement on knee pain in women over 50. This project expands on this and aims to investigate the composition of peptides absorbed from this supplement with particular interest in prolyl-hydroxyproline. The study will investigate the presence of peptides in the blood two hours after consumption of 15g of hydrolysed collagen suspended in 200mL water,
Interventions
Fasted participants will attend one visit to the Human Nutrition Research Unit at Massey University. After arrival at the research unit they will have 10mL venous blood drawn to determine baseline. The participant will then consume a drink of 15g collagen protein suspended in 200mL water. Two hours later, a second blood sample of 10mL will be collected. Blood samples will be drawn by a trained and experienced phlebotomist and participants monitored throughout their visit by one of the research t
Fasted participants will attend one visit to the Human Nutrition Research Unit at Massey University. After arrival at the research unit they will have 10mL venous blood drawn to determine baseline. The participant will then consume a drink of 15g collagen protein suspended in 200mL water. Two hours later, a second blood sample of 10mL will be collected. Blood samples will be drawn by a trained and experienced phlebotomist and participants monitored throughout their visit by one of the research team. Adherence will be determined by consumption of the full 200mL drink.
Sponsors
Massey University
Study design
Allocation
Non-randomised trial
Primary purpose
Prevention
Eligibility
Sex/Gender
All
Age
50 Years to No maximum
Healthy volunteers
Yes
Inclusion criteria
Healthy women over 50 years old
Exclusion criteria
BMI>26m/kg2, vegan/vegetarian (unwilling to consume gelatin or collagen), known osteoarthritis or probable OA-related pain in knee, hip etc., known connective tissue disorder (e.g., Rheumatoid arthritis, Scleroderma, Lupus, Polymyositis, Marfan’s Syndrome, Ehlers Danlos Syndrome).
Outcome results
None listed