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Risk factors for developing heart failure in people with obesity

Risk factors for developing heart failure in people with obesity

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ANZCTR
Registry ID
ACTRN12624000271505
Enrollment
4
Registered
2024-03-18
Start date
2025-03-28
Completion date
2026-04-01
Last updated
2025-09-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

Participants with a diagnosis of heart failure with preserved ejection fraction (HFpEF) will undergo a cardiac MRI to see if any structural heart changes can be used to predict those who are high-risk for progression of disease. Weight changes, hospitalizations, and symptom will be tracked every 6-months for a minimum of 3 years, and linking data with the National Death Index will allow us to identify patterns between heart failure and cardiac-related death. This data will allow the implementation of screening with MRI and early intervention for high-risk groups.

Interventions

Participants with a diagnosis of heart failure with preserved ejection fraction (HFpEF) will receive a cardiac MRI and have telephone follow-up 6-monthly for 3 years to observe changes in weight, symptoms, instances and frequency of hospitalizations, and any instances of death. The patients will have one in-person visit for CMR and baseline data. Follow-up will be a phone call at 6-monthly intervals for 3 years. If a participant dies during this time their data will be linked with the National

Participants with a diagnosis of heart failure with preserved ejection fraction (HFpEF) will receive a cardiac MRI and have telephone follow-up 6-monthly for 3 years to observe changes in weight, symptoms, instances and frequency of hospitalizations, and any instances of death. The patients will have one in-person visit for CMR and baseline data. Follow-up will be a phone call at 6-monthly intervals for 3 years. If a participant dies during this time their data will be linked with the National Death Index.

Sponsors

Baker Heart and Diabetes Institute
Lead SponsorOther Collaborative groups

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years
Healthy volunteers
No

Inclusion criteria

• Age 18-80 years • Fluent in English • Currently enrolled in the Alfred HFpEF clinic and have had an exercise RHC • Experiencing breathlessness • BMI >30kg/m2 • Eligible for Medicare (or equivalent health care insurance)

Exclusion criteria

• Type I or type II diabetes • Prior heart failure diagnosis • Pregnancy • Contraindication to MRI (metallic implant, foreign body/device)

Outcome results

None listed

Source: ANZCTR · Data processed: Feb 4, 2026