None listed
Conditions
Brief summary
Trials of calorie and protein delivery in critically ill patients have failed to show positive outcomes. However, these trials predominately intervene during the acute phase (first 7 days) of an Intensive Care Unit (ICU) admission only, where metabolic responses to critical illness are likely to impair nutrient utilisation. Furthermore, there is an increasing recognition that nutrition is not a short-term intervention, and extended nutrient provision is required to demonstrate benefit. Little is currently known about nutrition practices in patients that have a longer (>7 day) ICU stay. The purpose of the study is to describe nutrition practices in long-stay critically ill adult patients. 200 patients will be recruited at the Royal Adelaide Hospital. Data for all eligible patients will be extracted from the Australian New Zealand Intensive Care Society Adult Patient Database (ANZICS APD) where applicable, and additional data collected from the patient electronic medical record (EMR), bedside nursing staff, or the patient themselves. Data analysis will be conducted in SPSS Statistics software in consultation with qualified biostatistician Ms Kylie Lange from the National Health and medical Research Council (NHMRC) Centre for Research Excellence at The University of Adelaide. This prospective observational study is an integral step in defining key gaps in nutrition delivery to inform a program of research on improving patient recovery through optimal nutrition.
Interventions
The exposure observed is nutritional intake. Nutrition data will be collected daily for the first 14 days, and then every seven days thereafter (day 21, day 28), censored at day 28, death, or ICU discharge. All data is collected based on routine clinical practice, such that participants will receive nutrition intake regardless of their involvement in the study. Data will predominantly be collected from electronic medical records that is collected routinely in clinical practice. However if a pati
The exposure observed is nutritional intake. Nutrition data will be collected daily for the first 14 days, and then every seven days thereafter (day 21, day 28), censored at day 28, death, or ICU discharge. All data is collected based on routine clinical practice, such that participants will receive nutrition intake regardless of their involvement in the study. Data will predominantly be collected from electronic medical records that is collected routinely in clinical practice. However if a patient is orally fed, a 24-hour recall of their food intake. and nutrition symptoms will be collected directly from the patient.. At 90 days post study inclusion, the participant or next of kin will be contacted to obtain data on route of nutrition, nutrition intake from the previous 24 hours, presence of nutrition problems that impact nutrition intake or delivery, and an EQ-5D-5L health-related quality of life questionnaire.
Sponsors
Central Adelaide Local Health Network
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
1. Are admitted to the Royal Adelaide Hospital (RAH) ICU; 2. Are aged greater than or equal to 18 years; 3. Have an ICU length of stay of at least 5 days at time of screening and are anticipated to have a total ICU length of stay of at least 7 days as per the treating medical team.
Exclusion criteria
1. Readmitted to ICU within the current index hospital admission 2. Unable to obtain informed consent (no next of kin (NOK)/NOK unavailable/uncontactable).
Outcome results
None listed