None listed
Conditions
Brief summary
The supply of oxygen is essential for energy production, recovery from efforts, and human life. Intermittent Hypoxia-Hyperoxia Exposure (IHHE) is a novel technique in which the subject is exposed to a respiratory environment with reduced oxygen fraction, controlled through a specific software, using a facial mask and a hypoxic generation device. The objective of this study is to determine if there is a relationship between intermittent hypoxia-hyperoxia exposure and cardiorespiratory condition, blood pressure, and arterial oxygen saturation. According to our hypothesis, acute IHHE in elderly adults may influence cardiorespiratory condition, blood pressure, and arterial oxygen saturation. The study will be conducted as a randomized clinical trial. The subjects will be divided into two groups: the experimental group will undergo an IHHE session, breathing air with an oxygen concentration (FiO2) ranging from 10-14% for 1-5 minutes, with 1-3 minutes of rest in hyperoxia (FiO2 30-40%) for a total of 4-8 cycles, based on their acute response to hypoxia. The placebo group will undergo a 5-cycle protocol with an FiO2 of 21%.
Interventions
The EG (Experimental Group) will undergo asingle session of IHHE (Intermittent Hypoxia-Hyperoxia Exposure) session using the Energy/iAltitude® device (iAltitude Training S.L., Fuenlabrada, Madrid, Spain). They will breathe air with an oxygen concentration (FiO2) ranging from 10-14% for 1-5 minutes, followed by 1-3 minutes of rest in hyperoxia (FiO2 30-40%), for a total of 4-8 cycles, depending on their acute response to hypoxia.
Participants will be asked to sit and breath normally in each expo
The EG (Experimental Group) will undergo asingle session of IHHE (Intermittent Hypoxia-Hyperoxia Exposure) session using the Energy/iAltitude® device (iAltitude Training S.L., Fuenlabrada, Madrid, Spain). They will breathe air with an oxygen concentration (FiO2) ranging from 10-14% for 1-5 minutes, followed by 1-3 minutes of rest in hyperoxia (FiO2 30-40%), for a total of 4-8 cycles, depending on their acute response to hypoxia. Participants will be asked to sit and breath normally in each exposure. An attendance checklist will be used to monitor compliance with the intervention
Sponsors
Universidad Europea de Madrid
Study design
Allocation
Randomised controlled trial
Intervention model
Parallel
Primary purpose
Treatment
Masking
Blinded (masking used) (Subject, Investigator, Outcomes Assessor)
Eligibility
Sex/Gender
Male
Age
60 Years to 99 Years
Healthy volunteers
Yes
Inclusion criteria
• Being over 60 years old. • Having no previous experience in hypoxic training.
Exclusion criteria
• Having any pathology that prevents the performance of physical activity. • Subjects with impaired cognitive abilities. • Subjects with pulmonary hypertension, decompensated heart or respiratory failure. • Subjects who have undergone lower limb surgery within the past 12 months.
Outcome results
None listed