Skip to content

Assessing the impact of cleaning the surgical wound immediately after wound closure on bacterial growth on the skin

Effect of Surgical Site Cleaning on Bacterial Growth and Wound Disturbance in Patients undergoing Primary Total Hip and Knee Arthroplasty: A randomised controlled trial.

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ANZCTR
Registry ID
ACTRN12624000059561
Enrollment
130
Registered
2024-01-25
Start date
2023-07-18
Completion date
2024-05-31
Last updated
2024-01-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

To study the if cleaning the surgical wound immediately after wound closure causes increase in bacterial growth on the skin. This study includes patients undergoing elective total hip and total knee arthroplasty. Cleaning surgical site after wound closure is a common practice seen in operating theatres. In an attempt to remove dried body fluids from the skin, vigorous rubbing using surgical sponges is often required. Such a technique can introduce skin flora into the wash fluid and may risk a wound infection.

Interventions

Participants will be divided into 3 groups. There is only a single intervention performed in the operating theatre after the wound closure. Swabs will be taken by the operating surgeon after wound closure and sent to pathology on the special form approved for the trial. Swab results will be reviewed by the one of the associate investigators and record maintained under individual patient profile. In the first intervention group, surgical site will be cleaned with surgical sponge soaked in 30 m

Participants will be divided into 3 groups. There is only a single intervention performed in the operating theatre after the wound closure. Swabs will be taken by the operating surgeon after wound closure and sent to pathology on the special form approved for the trial. Swab results will be reviewed by the one of the associate investigators and record maintained under individual patient profile. In the first intervention group, surgical site will be cleaned with surgical sponge soaked in 30 ml sterile Chlorhexidine antiseptic solution, dried with a sterile sponge and swab taken from surgical site followed by application of sterile dressing. In the second intervention group, surgical site will be cleaned with surgical sponge soaked in 0.9 % Normal saline solution, then dried with a sterile sponge and swab taken from surgical site followed by application of sterile dressing.

Sponsors

Department of Orthopaedics
Lead SponsorHospital

Study design

Allocation
Randomised controlled trial
Intervention model
Parallel
Primary purpose
Prevention
Masking
Blinded (masking used) (Subject, Investigator, Outcomes Assessor)

Eligibility

Sex/Gender
All
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

1. Patients undergoing Primary Total Hip and Knee Arthroplasty 2. Patients should be able to provide consent either independently or through an interpreter

Exclusion criteria

Patients requiring revision surgery Patients with previous wound issues including wound or deep joint infection Patients with dermatological problems such as psoriasis or severe eczema or similar conditions that may affect skin healing potential.

Outcome results

None listed

Source: ANZCTR · Data processed: Feb 4, 2026