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Comparison of demographics, clinical symptoms, and urodynamic findings between detrusor overactivity with detrusor underactivity patients under the age of 70 and those aged 70 or older

Comparison of demographics, clinical symptoms, and urodynamic findings between detrusor overactivity with detrusor underactivity patients under the age of 70 and those aged 70 or older

Status
Completed
Phases
Unknown
Study type
Observational
Source
ANZCTR
Registry ID
ACTRN12624000008527
Enrollment
244
Registered
2024-01-09
Start date
2023-11-16
Completion date
2023-11-30
Last updated
2024-01-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

Detrusor overactivity with detrusor underactivity (DO-DU) is classically described in frail institutionalized elderly patients, but we have also observed this diagnosis in younger populations. This research attempts to retrospectively compare demographic characteristics, clinical presentations, and urodynamic findings between two age groups of DO-DU patients: those younger than 70 years and those aged 70 years or older. Our hypothesis predicts that the younger group would exhibit a higher prevalence of risk factors in their demographic data, while the elderly group will demonstrate a greater incidence of urgency and urge incontinence, likely attributed to limited mobility. Additionally, the urodynamic findings are expected to reveal less bladder contraction in the elderly group, which can be attributed to the effects of advanced age.

Interventions

This research retrospectively attempts to compare demographic characteristics, clinical presentations, and urodynamic findings between two age groups of detrusor overactivity with detrusor underactivity (DO-DU) patients: those younger than 70 years and those aged 70 years or older. This research is collecting data using a retrospective approach from medical records, absent any direct patient involvement. An approximate total of 250 patients diagnosed with DO-DU, who underwent multichannel urody

This research retrospectively attempts to compare demographic characteristics, clinical presentations, and urodynamic findings between two age groups of detrusor overactivity with detrusor underactivity (DO-DU) patients: those younger than 70 years and those aged 70 years or older. This research is collecting data using a retrospective approach from medical records, absent any direct patient involvement. An approximate total of 250 patients diagnosed with DO-DU, who underwent multichannel urodynamic testing at a single center from 2012 to 2023, were included in this study. Patients were divided into two groups: the “Younger” group (aged less than 70 years) and the “Older” group (aged 70 years or older). We compared demographics, number of risk factors considered to affect bladder function, clinical presentations, and urodynamic findings between these two groups using univariate statistical analysis.

Sponsors

Chiang Mai University
Lead SponsorUniversity

Eligibility

Sex/Gender
All
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

1. Over the age of 18 years underwent urodynamic study between 2012 and 2022. 2. Patient diagnosed with DO-DU from urodynamic study.

Exclusion criteria

1. A lack data for analysis. 2. Patients who have undergone intravesical botulinum toxin injections within the preceding 9 months.

Outcome results

None listed

Source: ANZCTR · Data processed: Feb 4, 2026