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Effect of prone position on mechanical power in patients undergoning neurosurgical operations

Prone position and mechanical power under general anesthesia

Status
Not yet recruiting
Phases
Unknown
Study type
Observational
Source
ANZCTR
Registry ID
ACTRN12623001281684
Acronym
PPMPUGA
Enrollment
60
Registered
2023-12-08
Start date
2024-01-01
Completion date
Unknown
Last updated
2024-01-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

This prospective observational designed study will be carried out on patients undergoing neurosurgical operations in prone position. The primary objective of the study is to determine the effect of prone position on mechanical power in prone position under general anesthesia. The secondary objective of the study is to determine the effect of patients' demographic data on the mechanical power in patients undergoing neurosurgical operations in prone postion under general anesthesia. the data will be collected 15 minutes after anesthesia induction in supine postion, 15 minutes after positioning the patient to prone position, hourly throughout till the end of surgery, at the end of surgery in prone position, and in supine position before waking up the patient.

Interventions

The effect of prone position on mechanical power will be investigated in patients undergoing neurosurgical operations under general anesthesia in prone position. The patient is positioned in the prone position as follows: The table is in a flat position. The arms are extended above the patient's head. The chest wall is supported by rollers that run from the pubic area to the collarbone.The support is placed under the pelvis. Knees and elbows are supported by pillows. The legs are bent up to knee

The effect of prone position on mechanical power will be investigated in patients undergoing neurosurgical operations under general anesthesia in prone position. The patient is positioned in the prone position as follows: The table is in a flat position. The arms are extended above the patient's head. The chest wall is supported by rollers that run from the pubic area to the collarbone.The support is placed under the pelvis. Knees and elbows are supported by pillows. The legs are bent up to knee level. The head is turned sideways and supported by a pillow so that there is no pressure on the eyes and ears. The arms are rotated backwards at torso level.The table is inclined to reduce lumbar lordosis. A belt is placed between the subgluteal region and the legs to prevent the patient from slipping caudally or cephalad. Various abdominal supports are placed to prevent pressure on the abdomen, such as tightly wrapped parallelepipeds, adjustable metal frames covered with soft supports, quadrupedal frames and more. Mechanical power refers to the energy delivered into the respiratory system and becomes particularly relevant during mechanical ventilation. Mechanical power is used to encapsulate potential lung injuries, such as barotrauma, atelectotrauma, and volutrauma, into a single value. These injuries often arise due to excessive pressure or volume changes within the lungs. Several parameters are employed in determining mechanical power: tidal volume , driving pressure , peak pressure , flow rate , respiratory rate, and PEEP . These data, recorded on the mechanical ventilation device and customized for the patient's condition, are analyzed using Gattinoni's formula for calculating mechanical power in volume-controlled ventilation: MP = TIDAL VOLUME X RESPIRATORY RATE X 0.098 X [ P PEAK – 1/2(P PLATEAU-PEEP)] This formula enables the calculation of mechanical power, providing insight into how much energy is imparted to the lungs and indicating the potential risk of damage. Mechanical power will be calculated as:15 minutes after anesthesia induction in supine position, 15 minutes after positioning the patient to prone position, and with 1 hour intervals therafter until the end of surgery and the last mechanical power calculations will be done at the end of the operation in prone position and concomittant with positioning the patient to supine before waking up the patient. Prone positioning will be done by the operation room personnel under the control of the anesthesiologist responsible for the care of the patient.

Sponsors

Berrak Sebil Aydin
Lead SponsorIndividual

Eligibility

Sex/Gender
All
Age
18 Years to 100 Years
Healthy volunteers
No

Inclusion criteria

patients undergoing neurosurgical operations in prone position aged 18-100 years with American Society of Anesthesiologist(ASA) physical classification score between ASA I - ASAIII,

Exclusion criteria

Patient refusal to be involved in the study, ASA physical classification score> III, patients with known organ insufficiency, patients with a history of prior respiratory system surgery, and morbid obesity.

Outcome results

None listed

Source: ANZCTR · Data processed: Feb 5, 2026