None listed
Conditions
Brief summary
This is a feasibility study with the aim of measuring the vitamin C status of people undergoing either a full or partial dental clearance. We will obtain data from 30 people with diabetes (PwD) and 30 people without diabetes who have been referred to the hospital outpatient dental department. Our primary objective is to determine the percentage of people undergoing dental clearance who are vitamin C deficient. We hypothesise that PwD will show evidence of hypovitaminosis C, though a smaller number of people without diabetes may also have low vitamin C levels.
Interventions
Surgical dental extraction. Fasting blood and urine collection on one occasion to measure paired vitamin C level. The collection of fasting samples will be at the patient's choice - either 1-2 days prior to the extraction appointment, or on the day of the procedure. They will be given food after the fasting samples have been collected.
Participants will be asked to complete a health related questionnaire during their extraction appointment.
Sponsors
Te Whatu Ora - Waitaha Canterbury
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Healthy volunteers
Yes
Inclusion criteria
People attending the hospital outpatient dental department for full and partial dental extractions (both groups) - Able to understand study and give full and informed consent - Agree to collection of age, ethnicity and health data - Willing / able to give a fasting blood and urine sample Group of 30 people without diabetes - HbA1c below 53 mmol/mol (7%) - not on any diabetes related medication - such as insulin, metformin, sulphonylurea's, DPPIV inhibitors, GLP1 receptor agonists or SGLT2 inhibitors Group of 30 people with diabetes - HbA1c of 53 mmol/mol (7%) or greater
Exclusion criteria
For both groups of participants: - Unable to fast prior to the sample collection - Unable to understand the informed consent or study requirements - Unwilling to participate
Outcome results
None listed