None listed
Conditions
Brief summary
Background The ReDO protocol is an abbreviation for ‘Repurposing Drugs in Oncology’, which is an ongoing worldwide project to find off-patent drugs that have anti-cancer effects. The ReDO protocol consists of multiple medication and nutrients, which are already approved by the FDA and TGA and have been used individually clinically for decades for a variety of clinical conditions. The Study This trial will be one of a number of clinical trials around the world to use a combination of medications and supplements to see if the ReDO protocol has any effects on cancer status. Each trial uses their own unique combination of medication and nutrients. This trial will use a combination of 19 medication and nutrients. Cancer status is measured by Circulating Tumour Cells (CTC) found in the blood, other cancer markers and standard diagnostic tools such as imaging. Who is it for? You may be eligible for this study if you are an adult who has been diagnosed with any cancer, and are able to come to the Willow Vale Clinic at the Gold Coast in QLD. Study details All participants in this study will be asked to commence use of 19 medications/supplements, one at at time, over a period of two months. Once participants have successfully used all medications/supplements, they will continue to take these for three to six months. Throughout this time, participants will be followed up via blood tests, scans, and questionnaires to monitor side effects, cancer status and quality of life. It is hoped that this study will systematically investigate the effectiveness of the updated ReDO protocol, consisting of 19 medication and nutrients, on cancer cell count, a biomarker for cancer status togather with other standard diagnostic tests.
Interventions
The REDO Protocol consists of 19 medication (a) and nutrients (b) , introduced one item at the time, each item 3 days apart with side effects monitored over a period of 2 months. The full ReDO protocol (19 items) consists of the following dosages per day administered for 3 months (90 days).
All items are administered as oral tablets, with the exception of item 19, which is provided as oil.
Order of items in 2 month introduction period / Item / Dosage per day:
a) Prescription medication
1 Dic
The REDO Protocol consists of 19 medication (a) and nutrients (b) , introduced one item at the time, each item 3 days apart with side effects monitored over a period of 2 months. The full ReDO protocol (19 items) consists of the following dosages per day administered for 3 months (90 days). All items are administered as oral tablets, with the exception of item 19, which is provided as oil. Order of items in 2 month introduction period / Item / Dosage per day: a) Prescription medication 1 Dichloroacetate 500 mg x2 2 Propanolol 40mg x 2 3 Metformin 500 mg x 1; 500 mg x 2 4 Atorvastatin (+ CoQ10) 20 mg/ night; 2x 20 mg 7 Sodium Phenylbutyrate 1-4 g/ night 8 Dipyridamole 2x 100 mg/ day; 2x200 mg 9 Hydroxychloroquine 200 mg /night 10 Ivermectin 25 mg/night 11 Melatonin 100mg 12 Doxycycline 50 mg x2 13 Mebendazole / Fenbendazole 100 mg x2 17 Loratadine (Anti-histamine) 20 mg x 2 b) Natural herbal supplements 5 Genistein 100mg x 3 6 D-Mannose 2x 1000 mg 14 Vitamin A (Retinoic Acid) 35,000 IU - 1 week on 1 week off 15 Berberine 2x 500mg 16 Epigallocatechin Gallate (EGCG) = green tea extract 400 mg x2 18 Hydroxy-citrate (Garcinia cambogia) 1000 mg x 2 19 Nigella Sativa Black Seed Oil 5ml x2 Compliance will be monitored by an online participant diary app.
Sponsors
Dr Taufiq Binjemain
Study design
Allocation
Non-randomised trial
Intervention model
Single group
Primary purpose
Treatment
Masking
Open (masking not used)
Eligibility
Sex/Gender
All
Age
20 Years to No maximum
Healthy volunteers
No
Inclusion criteria
diagnosed with cancer suggested for the ReDO protocol by the investigating doctor
Exclusion criteria
planning to start cancer treatments other than the ReDO protocol in the next 5 months
Outcome results
None listed