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Randomised controlled trial of an online ultra-brief treatment for depression and anxiety for people with depression or anxiety

A randomised controlled trial of an online ultra-brief treatment for depression and anxiety symptoms in adults with a diagnosed depressive or anxiety disorder

Status
Completed
Phases
Unknown
Study type
Interventional
Source
ANZCTR
Registry ID
ACTRN12623001075673
Enrollment
188
Registered
2023-10-09
Start date
2024-01-19
Completion date
2024-12-10
Last updated
2025-10-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

Our previous research found that an ultra-brief online treatment was effective for managing depression and anxiety symptoms. This research trial is testing how quickly people with a diagnosed depressive or anxiety disorder benefit from an ultra-brief treatment. People will be randomly allocated to receive access immediately or after a 4-month waiting period. Questionnaires will be administered every 2 weeks for 4 months. The primary endpoint is Week 17 and we expect that the treatment will result in larger reductions in depression and anxiety compared to the control.

Interventions

A two arm randomised controlled trial. Participants will be randomised to treatment or a waitlist control group. The treatment itself consists of a single online lesson which provides psychoeducation about the nature of anxiety and depression, recommendations for self-management of symptoms, and one week of optional contact with a clinician from the eCentreClinic. This intervention will also include practice exercises, illustrative case examples, and an additional resource on managing worry an

A two arm randomised controlled trial. Participants will be randomised to treatment or a waitlist control group. The treatment itself consists of a single online lesson which provides psychoeducation about the nature of anxiety and depression, recommendations for self-management of symptoms, and one week of optional contact with a clinician from the eCentreClinic. This intervention will also include practice exercises, illustrative case examples, and an additional resource on managing worry and problem solving. It is expected that participants will take 60 minutes to read the lesson, read the practice exercises and resource, and read the case stories. Additional skills practice is at the discretion of the participant. The materials consist of PDF and static powerpoint slides (i.e., no video or audio). Adherence will be measured by tracking the number of times a participant views or downloads each document. The psychologist will contact participants to arrange a telephone call within a week of this lesson being released. Participants will be able to speak over the phone with the psychologist within a week of the participant viewing the lesson (i.e., this contact is not limited to the week that the treatment becomes available to accommodate participant availability). There is no time limit to this telephone consult or private messages, although it is expected that phone consults will be 20-30 minutes long. The purpose of this contact is to reinforce the lesson content, support the participant to use the skills, and answer any questions they may have. Additional contact outside this week will be made if participants indicate that they are at risk of suicide/ self-harm or are experiencing technical difficulties.

Sponsors

Macquarie University
Lead SponsorUniversity

Study design

Allocation
Randomised controlled trial
Intervention model
Parallel
Primary purpose
Treatment
Masking
Open (masking not used)

Eligibility

Sex/Gender
All
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

(a) Australian resident (b) Are aged 18 years or older (c) Meets diagnostic criteria for a depressive or anxiety disorder

Exclusion criteria

(a) Actively suicidal or unable to keep themselves safe (b) Living outside of Australia (c) Unable to read and understand English.

Outcome results

None listed

Source: ANZCTR · Data processed: Feb 4, 2026