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The effects of simulated altitude on the physiological responses of older adults to strength training.

The effects of normobaric hypoxia on the physiological responses of older adults to resistance exercise.

Status
Completed
Phases
Unknown
Study type
Interventional
Source
ANZCTR
Registry ID
ACTRN12623001046695
Enrollment
20
Registered
2023-09-27
Start date
2017-02-06
Completion date
2019-10-15
Last updated
2023-10-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

This study aims to determine if performing strength training in simulated altitude can cause greater improvements in muscle strength and muscle size in older adults, compared to traditional strength training at sea level conditions. The study ultimately aims to help slow the progression of muscle weakness and muscle wasting in older adults. We hypothesise that performing strength training in simulated altitude (termed hypoxia) will enhance the muscle training responses compared to training at sea level.

Interventions

Participants complete either 8 weeks of strength training in normal environmental conditions (sea level; normoxia) or 8 weeks of strength training in simulated altitude (nornobaric hypoxia). Hypoxia was generated using a nitrogen enriching machine, that replaced a fraction of oxygen with nitrogen. The selected hypoxia was 14.4% to simulate an altitude of approximately 3,300m above sea level. A trained exercise scientist supervised each training session in a one-on-one session at the University

Participants complete either 8 weeks of strength training in normal environmental conditions (sea level; normoxia) or 8 weeks of strength training in simulated altitude (nornobaric hypoxia). Hypoxia was generated using a nitrogen enriching machine, that replaced a fraction of oxygen with nitrogen. The selected hypoxia was 14.4% to simulate an altitude of approximately 3,300m above sea level. A trained exercise scientist supervised each training session in a one-on-one session at the University gymnasium. Resistance exercise was performed at 70% of 1 repetition maximum (1RM), using four exercises: leg extension, pectoral fly, standing row and squat. Participants completed 2 sessions weekly for 8 weeks. Each session was approximately 60 minutes in duration.

Sponsors

Deakin University
Lead SponsorUniversity

Study design

Allocation
Randomised controlled trial
Intervention model
Parallel
Primary purpose
Prevention
Masking
Blinded (masking used) (Subject)

Eligibility

Sex/Gender
All
Age
60 Years to 75 Years
Healthy volunteers
Yes

Inclusion criteria

Healthy adults (male and female) aged 60-75 years old. Participants must be free of diagnosed cardiovascular and respiratory conditions to be included in the study.

Exclusion criteria

Diagnosed cardiovascular or respiratory condition, musculoskeletal disorder that prevents participant from completing strength training, blood condition (eg. abnormal white blood cell count or anemia).

Outcome results

None listed

Source: ANZCTR · Data processed: Feb 8, 2026