None listed
Conditions
Brief summary
We aim to determine if maternal oxygen supplementation 5-10 min prior to birth of term and near-term infants (32 weeks gestation or above at birth) utilising heated humidified high flow nasal cannula with 100% oxygen at 30-70L/min is feasible at both caesarean section and vaginal births. The information gained from this feasibility study will inform the planned randomised controlled trial of maternal oxygen in very preterm infants.
Interventions
Maternal oxygen supplementation via heated humidified high flow nasal cannula for 5-10 minutes at 100% oxygen at 30-70L/min before umbilical cord is clamped. Adherence will be monitored in person by one of two principal investigators and will be documented in study database
Sponsors
Douglas Blank
Study design
Allocation
Non-randomised trial
Primary purpose
Prevention
Eligibility
Sex/Gender
All
Age
18 Years to 50 Years
Healthy volunteers
No
Inclusion criteria
Expecting women between 32 weeks and 0 days to 41 weeks and 6 days gestational age giving birth
Exclusion criteria
History of severe maternal epistaxis History of major nasal/sinus surgery or pathology Concurrent maternal chronic obstructive pulmonary disease (COPD) exacerbation Fetus with congenital abnormality that would alter the expected SpO2 targets in the minutes after birth; ie antenatal diagnosis of ductal dependant cardiac lesions, congenital diaphragmatic hernia, etc. Monochorionic twins with evidence of twin-to-twin transfusion syndrome or multiples of more than 2.
Outcome results
None listed