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Paediatric Asthma and Wheeze Study - Part 1

Using a wheeze scan device (WheezeScan) for the management of preschool wheeze and paediatric asthma: a multicentre cohort study - Part 1

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ANZCTR
Registry ID
ACTRN12623000904673
Acronym
PAWS-1
Enrollment
4
Registered
2023-08-23
Start date
2024-02-01
Completion date
2027-07-31
Last updated
2024-04-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

Wheeze, a breath sound that may indicate asthma, is very common in children; ~50% of all preschool aged children have an episode of wheeze and 40% of these children have recurrent wheeze. Also, asthma is the most common chronic illness in children. Yet, identifying wheeze is challenging for parents (disagreement rate between doctors and parents are >50%) and indeed many cultures (including Indigenous Aus) do not have a word for wheeze. Our multicentre study addresses the need to define wheeze accurately using digital technology. We will use WheezeScan (WzS) digital technology during face-to-face clinics as well as remotely (child’s home) in Queensland (including outreach clinics), Darwin and Sydney. Recruiting children from the hospitals and outreach clinics, we plan a cohort study involving 102 preschool children suspected of having asthma. We aim to determine whether using WzS improves the diagnosis of asthma, patient related outcomes (PROs) and health cost. WzS’s dependable accuracy will provide parents/caregivers and doctors the ability to discern if a child is wheezing-subsequently providing the confidence and clarity over the next steps that need actioning. Our study will improve the detection and consequently the management of preschool wheeze by the accurate diagnosis of reversible airway obstruction/asthma. Our proposal will fulfil a large unmet clinical need and research gap, identified by our patients, parents, parent advisory group, clinicians, Asthma Foundation of NT, as well as Australian data and international surveys.

Interventions

Use of WheezeScan (WzS), a portable user-friendly digital device that listens to 30sec of breathing then objectively documents wheeze using AI-informed signal processing. WzS is manufactured by Omron (Japan). Parents will be trained by the research nurses/assistants using a standard protocol provided by the manufacturers (sse link https://www.omron-healthcare.co.uk/nebulisers/wheezescan.html). Adherence will be monitored using participant diaries. Wheezescan will be used at least once a day ov

Use of WheezeScan (WzS), a portable user-friendly digital device that listens to 30sec of breathing then objectively documents wheeze using AI-informed signal processing. WzS is manufactured by Omron (Japan). Parents will be trained by the research nurses/assistants using a standard protocol provided by the manufacturers (sse link https://www.omron-healthcare.co.uk/nebulisers/wheezescan.html). Adherence will be monitored using participant diaries. Wheezescan will be used at least once a day over the study period of 5 weeks.

Sponsors

Queensland University of Technology
Lead SponsorUniversity

Study design

Allocation
Non-randomised trial
Primary purpose
Diagnosis

Eligibility

Sex/Gender
All
Age
6 Months to 6 Years
Healthy volunteers
No

Inclusion criteria

Children (aged 0.5 to 6 yrs) reviewed for suspected asthma (e.g. 2 or more reported wheeze episodes, chronic (>4 weeks) cough, or exertional breathlessness).

Exclusion criteria

Presence of (a) suspected chronic suppurative lung disease eg. chronic wet cough, (b) previous respiratory specialist-diagnosed asthma, (c) previously enrolled or (d) unable to complete PROs.

Outcome results

None listed

Source: ANZCTR · Data processed: Feb 4, 2026