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A comparison of health complications arising 12 months after a PCR-positive test for COVID-19, influenza, and respiratory syncytial virus.

A retrospective analysis of existing epidemiological data that compares health complications arising 12 months after a PCR-positive test for COVID-19, influenza, and respiratory syncytial virus.

Status
Completed
Phases
Unknown
Study type
Observational
Source
ANZCTR
Registry ID
ACTRN12623000810617
Enrollment
377000
Registered
2023-07-27
Start date
2024-12-01
Completion date
2025-03-01
Last updated
2026-01-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

This research project aims to: a) To examine the risks of subsequent health complications (determined by ICD-10AM code) in the 12 months following COVID-19, influenza or RSV infection, compared with a control group (no recent evidence of COVID-19 or influenza infection). b) inform Queensland Health about the potential scale of post-viral impacts arising from COVID-19 or influenza, and any system-wide response that may be required. The Project Team is part of the Office of the Chief health Officer in Queensland Health, which accesses the Notifiable Conditions System. The system houses information on COVID-19, influenza and RSV-positive PCRs.

Interventions

Eligible participants are those who received a PCR-positive test result for COVID-19, influenza, or respiratory syncytial virus (RSV) from 1 July 2017. Not all participants are tested for these illnesses simultaneously, meaning that COVID-19 positive cases are included if they were not also tested for influenza and RSV (and vice-versa), however these are small in number. For patients with a record of a positive or negative via PCR test to COVID-19 in Qld's Notifiable Conditions System to 30 Jun

Eligible participants are those who received a PCR-positive test result for COVID-19, influenza, or respiratory syncytial virus (RSV) from 1 July 2017. Not all participants are tested for these illnesses simultaneously, meaning that COVID-19 positive cases are included if they were not also tested for influenza and RSV (and vice-versa), however these are small in number. For patients with a record of a positive or negative via PCR test to COVID-19 in Qld's Notifiable Conditions System to 30 June 2023, they will be observed for 12 months after this test to determine whether they experience a subsequent health event demonstrated by being assigned an ICD-10 code/s (specific codes are listed in the protocol). For patients with a record of a positive via PCR test to influenza in Qld's Notifiable Conditions System to 30 June 2023, they will be observed for 12 months after this test to determine whether they experience a subsequent health event demonstrated by being assigned an ICD-10 code/s (specific codes are listed in the protocol). For patients with a record of a positive via PCR test to RSV in Qld's Notifiable Conditions System to 30 June 2023, they will be observed for 12 months after this test to determine whether they experience a subsequent health event demonstrated by being assigned an ICD-10 code/s (specific codes are listed in the protocol). As a result, there is no active participation, but rather analysis of medical records to ascertain impacts arising from exposure. This utilises the analysis of ICD-10 codes, with a full list provided in the attached study protocol.

Sponsors

Queensland Health
Lead SponsorGovernment body

Eligibility

Sex/Gender
All
Age
0 to No maximum
Healthy volunteers
No

Inclusion criteria

People who had a PCR positive test result for COVID-19, influenza, or RSV which was recorded in the QLD Health Notifiable Conditions System.

Exclusion criteria

As an epidemiological study of the impacts of COVID-19, influenza and RSV on the Queensland population, there are no proposed exclusions for those with a record of COVID-19 or influenza testing in NoCS from 1 July 2017 to 30 June 2023.

Outcome results

None listed

Source: ANZCTR · Data processed: Feb 4, 2026