None listed
Conditions
Brief summary
In patients who will undergo open thoracic surgery, two different types of drugs will be administered to volunteer patients before surgery in order to relieve postoperative pain, facilitate breathing and reduce hospitalization time. The pain intensity, respiratory capacity, the amount of opioid analgesic needed during and after surgery, side effects such as nausea-vomiting, low blood pressure and shortness of breath will be evaluated.
Interventions
Group TEA (Thoracic Epidural Analgesia): Thoracic Epidural Application: The epidural area will be accessed from the 7th (T7)-8th (T8) level of the thoracic vertebral midline with an 18 gauge (G) epidural needle using the hanging drip technique. After 2 ml of 2% lidocaine is administered and no spinal effect is observed, a mixture of morphine and local anaesthetic 3-4 mg morphine hydrochloride + 5 ml 0.5% bupivacaine + 2 ml 0.9% saline will be administered through the epidural needle at once and
Group TEA (Thoracic Epidural Analgesia): Thoracic Epidural Application: The epidural area will be accessed from the 7th (T7)-8th (T8) level of the thoracic vertebral midline with an 18 gauge (G) epidural needle using the hanging drip technique. After 2 ml of 2% lidocaine is administered and no spinal effect is observed, a mixture of morphine and local anaesthetic 3-4 mg morphine hydrochloride + 5 ml 0.5% bupivacaine + 2 ml 0.9% saline will be administered through the epidural needle at once and the epidural needle will be withdrawn and sterile dressing will be applied. - The mode of presentation will be face-to-face and individually. - The intervention will be performed by an anaesthetist with at least 5 years of experience. - The stages of the intervention will be verbally explained in detail to participants prior to the intervention. - The patient will be taken to the operating table and electrocardiographic, oxygen saturation with psilse oximetry and non-invasive blood pressure monitoring with automatic manometer will be performed. - The intervention will be administered only once, 3-4 mg of morphine hydrochloride + 5 ml of 0.5 % bupivacaine + 2 ml of 0.9 % saline into the epidural space. - Immediately before induction of anaesthesia, the patient will be seated and after appropriate sterilisation conditions are provided, the thoracic epidural space will be reached and the analgesic mixture will be given once and the space will be exited. - Immediately after sterile dressing of the intervention site, the patient will be placed supine and standard general anaesthesia will be applied. - The intervention will be performed in the thoracic surgery room of our hospital operating theatre.
Sponsors
Health Sciences University Training and Research Hospital
Study design
Allocation
Randomised controlled trial
Intervention model
Parallel
Primary purpose
Treatment
Masking
Blinded (masking used) (Subject, Investigator, Outcomes Assessor)
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Healthy volunteers
No
Inclusion criteria
Volunteer patients aged 18-70 years, American Society of Anesthesiologists (ASA) I-III physical status, who were to undergo thoracotomy were included in the study.
Exclusion criteria
Patients with infection in the application area, coagulation disorder, morbid obesity (Body Mass Index (BMI > 35), drug allergy, chronic pain history, long-term opioid use, psychiatric disease history, emergency operations and patients who did not agree to participate in the study were excluded from the study
Outcome results
None listed