Skip to content

Comparison of the efficacy of modified thoracolumbar interfacial plane block (mTLIP) and erector spinae plane block (ESP) for preemptive analgesia in lumbar discectomy surgery

Comparison of the effects of modified thoracolumbar interfacial plane (mTLIP) block and erector spina plane block on postoperative pain and opioid analgesic consumption in patients undergoing lumbar discectomy for lumbar disc herniation

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ANZCTR
Registry ID
ACTRN12623000750684
Enrollment
38
Registered
2023-07-11
Start date
2023-06-21
Completion date
Unknown
Last updated
2023-07-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

Patients who will undergo herniated disc surgery have serious pain after surgery. In order to minimise this pain and to ensure that they recover more quickly and use less morphine-derived painkillers, we aim to apply two types of painkiller injections before surgery. For this purpose, it is planned to apply painkiller injections on both sides of the level of the herniated disc with sedation before the operation. Afterwards, herniated disc surgery will be performed under general anaesthesia. Previous studies have shown that these applications reduce postoperative pain and discomfort and increase patient satisfaction. In addition, it has been shown that they need less intravenous morphine-derived painkillers.

Interventions

Modified thoracolumbar plane block (mTLIP): under ultrasound-guided, the lateral compartment of the longissimus muscle and iliocostal muscle muscles are imagined and the block needle is placed in the interfascial plane of these two muscles and local anesthesic solution is appliced. - 20 ml of 0.25% bupivacaine will be used on each side (total of 40 ml of 0.25% bupivacaine will be used) - to be administered only approximately 20-30 minutes before the onset of anaesthesia. - only once in the pr

Modified thoracolumbar plane block (mTLIP): under ultrasound-guided, the lateral compartment of the longissimus muscle and iliocostal muscle muscles are imagined and the block needle is placed in the interfascial plane of these two muscles and local anesthesic solution is appliced. - 20 ml of 0.25% bupivacaine will be used on each side (total of 40 ml of 0.25% bupivacaine will be used) - to be administered only approximately 20-30 minutes before the onset of anaesthesia. - only once in the preoperative block room approximately 20-30 minutes before induction of anaesthesia - plane block applications will be performed by anaesthesiologists with at least 5 years of experience - patients' intraoperative fentanyl consumption, agitation-sedation scores on awakening from anaesthesia, tramadol consumption in the postoperative 24 hours, postoperative VAS pain scores, and side effects such as postoperative nausea-vomiting will be evaluated. - plane blocks will be applied under ultrasound guidance. - plane block applications will be performed by anaesthesiologists with at least 5 years of experience - Postoperative evaluations of patients will be performed face to face. Patients will be routinely administered 1 g paracetamol intravenously at 8 hour intervals in the postoperative period. 100 mg tramadol intravenously will be administered if their pain is above VAS 4 despite this. - This study was followed up in the neurosurgery unit of SBU Gazi Yasargil Training and Research Hospital. - Patients were sedated with 1 mg midazolam and 50 mcg fentanyl intravenously in the preoperative preparation room in the operating room and 20 ml of 0.25% bupivacaine was administered bilaterally on each side under ultrasound guidance. After the block application, the patient was taken to the operating room and standard general anaesthesia was applied. Patients will be monitored for pain and side effects at the neurosurgery unit , 1st hour, 2nd hour, 4th hour, 8th hour and 24th hour in the postoperative period. - Both plan blocks are applied for analgesia in the postoperative period and aim to reduce opioid consumption in the postoperative period.

Sponsors

Health Sciences University Training and Research Hospital
Lead SponsorUniversity

Study design

Allocation
Randomised controlled trial
Intervention model
Parallel
Primary purpose
Prevention
Masking
Blinded (masking used) (Subject, Investigator, Outcomes Assessor)

Eligibility

Sex/Gender
All
Age
18 Years to 70 Years
Healthy volunteers
No

Inclusion criteria

Patients between 18-70 years of age, ASA I-III, scheduled for Lumbar Disc Herniation operation under general anaesthesia.

Exclusion criteria

ASA >III body mass index (BMI) > 35 kg/m2 known allergy to local anaesthetics presence of preoperative chronic pain presence of coagulopathy those who are unable to give written consent non-voluntary patients

Outcome results

None listed

Source: ANZCTR · Data processed: Feb 4, 2026