None listed
Conditions
Brief summary
It is aimed that patients who will undergo laparoscopic gallbladder surgery will experience less pain after surgery and require less morphine-derived painkillers. In relation to this, it is expected to reduce the risk of side effects such as nausea, vomiting, shoulder pain, shortness of breath after surgery. To achieve this, we aim to determine the most effective and long-lasting pain relief method. For this reason, a total of 128 patients between the ages of 18-70 who will undergo gallbladder surgery were planned to be included in the study, including one group of patients with transabdominis plane block (TAPB), one group of patients with Quadratus lumborum plane block (QLB) and one group of patients with intravenous painkillers (IVA). In addition to postoperative agitation assessment and visual pain assessment at 30 minutes, 2, 4, 12 and 24 hours, possible side effects such as nausea, vomiting, shoulder pain, respiratory distress, pulse and blood pressure drop will be observed and recorded. In addition, the total amount of morphine-derived painkillers consumed in the first 24 hours after surgery and the duration of hospital stay will be observed and recorded.
Interventions
1-Group QLB (quadratus lumborum plane block): 20 ml of 0.25% bupivacaine will be used each time for plane block on both sides
2- Group TAPB (transverse abdominis plane block): 20 ml of 0.25% bupivacaine will be used each time for plane block on both sides
- Medical records will be audited to monitor adherence to the intervention.
-each patient will be administered 0.25% bupivacaine for each side (a total of 40 ml of 0.25% bupivacaine will be used)
- plane blocks will be applied under ultrasoun
1-Group QLB (quadratus lumborum plane block): 20 ml of 0.25% bupivacaine will be used each time for plane block on both sides 2- Group TAPB (transverse abdominis plane block): 20 ml of 0.25% bupivacaine will be used each time for plane block on both sides - Medical records will be audited to monitor adherence to the intervention. -each patient will be administered 0.25% bupivacaine for each side (a total of 40 ml of 0.25% bupivacaine will be used) - plane blocks will be applied under ultrasound guidance. - plane block applications will be performed by anaesthesiologists with at least 5 years of experience - Postoperative evaluations of patients will be performed face to face. - Plane block applications will be applied only once in the preoperative period. - Patients will be routinely administered 1 g paracetamol intravenously at 8 hour intervals in the postoperative period. 100 mg tramadol intravenously will be administered if their pain is above Visual Analogue Scale (VAS) 4 despite this. - This study will be followed up in the general surgery unit of Health Sciences University Gazi Yasargil Training and Research Hospital. - Patients will be sedated with 1 mg midazolam and 50 mcg fentanyl intravenously in the preoperative preparation room in the operating room and 20 ml of 0.25% bupivacaine was administered bilaterally on each side under ultrasound guidance. After the block application, the patient was taken to the operating room and standard general anaesthesia was applied. Patients will be monitored for pain and side effects at 30th minute, 2nd hour, 4th hour, 12th hour and 24th hour in the postoperative period. - Both plane blocks are applied for analgesia in the postoperative period and aim to reduce opioid consumption in the postoperative period.
Sponsors
Fatma Acil
Study design
Allocation
Randomised controlled trial
Intervention model
Parallel
Primary purpose
Prevention
Masking
Blinded (masking used) (Subject, Investigator, Outcomes Assessor)
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Healthy volunteers
No
Inclusion criteria
Aged 18-70 years, who will undergo laparoscopic cholecystectomy and who meet the ASA1-3 risk classification
Exclusion criteria
ASA above 3 Age < 18 or >70 years patient's reluctance
Outcome results
None listed