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Effects of transcranial and peripheral magnetic stimulation on quadriceps strength,muscle activation and pain recovery after and intense eccentric exercise causing delayed onset muscle soreness to young athletes

“Effects of combined treatment with peripheral electromagnetic stimulation and transcranial electromagnetic stimulation on recovery from late-onset muscle damage induced by eccentric exercise in young athletes. A randomized clinical trial”

Status
Not yet recruiting
Phases
Unknown
Study type
Interventional
Source
ANZCTR
Registry ID
ACTRN12623000677606
Enrollment
96
Registered
2023-06-23
Start date
2023-07-10
Completion date
2023-07-17
Last updated
2023-07-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

Delayed Onset Muscle Soreness (DOMS) is a recurring problem in sports, coaches and clinicians investigate its origin and try to find strategies to improve DOMS symptoms. Regarding the symptoms described DOMS can lead to a loss of joint amplitude up to 50%, as well as the force generated by the muscle,pain that is related to micro damage to muscle fibers induced by eccentric exercise. They also usually report a feeling of weakness that comes from the inflammation that appeared in the second phase. The most common is that they appear in a return to activity or in front of an unusual exercise, which generates a feeling of discomfort that can go as far as a decrease in performance, even the loss of the athlete. These symptoms usually lasts around 72 hours. Due to the new theories about DOMS an it relationship with the peripheral and central nervous system, our hypothesis is that The combination of Peripheral Electromagnetic Stimulation therapy and Transcranial Electromagnetic Stimulation could improve performance through peripheral and central nervous system recovery in young athletes suffering from late-onset muscle soreness induced by eccentric exercise. After a protocol of eccentric exercise perform by healthy male athletes we will check the DOMS measuring the levels of creatinkinase and lactate in blood. The athletes will perform a dynamometric strength test, a CMJ test, a Half squat test, 30 meter sprint and we will record the EMG of the quadriceps to check activation and the heart rate variability. The athletes will be treated daily using peripheral or transcranial magnetic stimulation, a combination of both or a placebo. they will also be measured daily to see how the outcomes behave during the 3 days recovery period. We will have 4 groups measured 5 times

Interventions

The subjects will have to undergo a common and generalized warm-up before starting the eccentric exercises. The warm-up is comprised of standing hip and knee mobility along with ballistic stretches for the quadriceps and hamstrings. Then, one set of skipping followed by one set of 10 reps of bodyweight squats and one set of bodyweight lunges. The protocol is based on the study by (Howatson et al., 2012). Once the warm-up is done, the subjects will have to perform 3 eccentric exercises focused on

The subjects will have to undergo a common and generalized warm-up before starting the eccentric exercises. The warm-up is comprised of standing hip and knee mobility along with ballistic stretches for the quadriceps and hamstrings. Then, one set of skipping followed by one set of 10 reps of bodyweight squats and one set of bodyweight lunges. The protocol is based on the study by (Howatson et al., 2012). Once the warm-up is done, the subjects will have to perform 3 eccentric exercises focused on the quadriceps within which there will be: - 10 series of 10 repetitions of squats at 60% of the 1 RM. Said load was calculated before the study to facilitate the performance and understanding of the procedure by the subjects. Which series will be performed with the help of a Smith Multipower Bar guide machine so that there are no parasitic movements and focus the work on the quadriceps. - 3 series of 10 repetitions per leg of the Bulgarian squat. Subjects may add up to 10 kilos depending on how they will feel after squats, this possible change will have to be specified before the start of the exercise. - 3 series of 10 repetitions per leg of Strides, likewise with possible added load by prior request of the subject depending on how he will be after the first 2 exercises. The rest times will always be the same, that is, 2 minute rest between series and series. As for the rest between exercises, they will be left 4 minutes so that they have enough strength to finish the entire session. All the exercises and the warm up will be supervised by a strength and condition trainer and a sports physical therapy expert. Afterwards, once they have finished the eccentric protocol they will go to the group they belong to. -The first group will be treated just after they finished the eccentric exercise circuit,24,48 and 72 hours after the exercises, with transcranial magnetic stimulation (MAGREX)on Motor cortex (2000 pulses at 10 hz, 90% of the motor threshold calculated after finding the motor threshold which is an evoke potencial over 50 microvolts repeated at least 5. out of 10 times) (ARM 1).The treatment will be delivered by an expert physical therapist with more than 10 years of experience in this technique. -second group will be treated after they finished the eccentric exercise circuit,24,48 and 72 hours after the exercises, with a peripheral magnetic stimulation (MAGREX). 5 stimulations at a sensitive threshold (subject must report that he feels the current) over the femoral nerve of the dominant leg the athlete. Each stimulation will last 5 seconds with a 55 second period rest. (ARM2). The treatment will be delivered by an expert physical therapist with more than 10 years of experience in this technique. - third group will be treated with the combination of both techniques after they finished the eccentric exercise circuit,24,48 and 72 hours after the exercises. First the trancranial magnetic stimulation protocol followed by the peripheral stimulation.(arm3). The treatment will be delivered by an expert physical therapist with more than 10 years of experience in this technique.

Sponsors

Universidad Europea de Madrid
Lead SponsorUniversity

Study design

Allocation
Randomised controlled trial
Intervention model
Parallel
Primary purpose
Prevention
Masking
Blinded (masking used) (Subject, Investigator, Outcomes Assessor)

Eligibility

Sex/Gender
Male
Age
18 Years to 35 Years
Healthy volunteers
Yes

Inclusion criteria

Men between 18-35 years old. • Practice sports activity at least 3 times a week for at least a year. • Not having undergone surgery on the lower limb during the past 12 months. • Not be a smoker. • Not suffer a desensitization of the areas that will be treated with peripheral stimulation. • Not having a pathology diagnosed as a chronic disease. • Not having had a musculoskeletal injury in the lower extremities in the last 6 months.

Exclusion criteria

Suffer desensitization in treatment areas with both peripheral and transcranial electromagnetic stimulation. • Having some pathology that prevents physical activity. • Subjects who would not have full cognitive abilities.

Outcome results

None listed

Source: ANZCTR · Data processed: Feb 4, 2026