IMAGENDO: Diagnosing Endometriosis with Imaging and Artificial Intelligence

There are two study arms: Stage 1 - retrospective study - Women who have had an MRI or MRI and TV-US in the last 5 years will be contacted directly by mail by administration staff from our partner radiology and ultrasound clinics (including Benson Radiology, Specialist Imaging Partners, OmniGynaecare, O &G ) to obtain consent for these images and to follow up on any operation notes to confirm diagnosis. It is anticipated that it will take approximately 25 – 35 mins for the participant to complete their baseline data collection. Baseline data collection includes date of birth, height and weight, any previous surgery, any previous diagnostic imaging, Treating Specialist Doctor / Gynaecologist, Surgeon name and Hospital. Images and operation notes are de identified by admin staff from the clinic before being sent to the computer analysts. Participants will only need to read information and provide consent, and supply baseline information including date of birth, height and weight, any previous surgery, any previous diagnostic imaging, Treating Specialist Doctor / Gynaecologist, Surgeon name and Hospital. Once imaging and operation notes are received there will be no further observation. Images and medical history details will be entered into a machine learning algorithm designed specifically for this study. We will then compare the results from the algorithm to the documented diagnosis. Stage 2: After being identified as eligible for the study, if they haven’t already had one, women will be invited to undertake a transvaginal endometriosis ultrasound scan and/or an MRI at one of the imaging partners. These scans take less than an hour to complete. They will then attend a follow up interview with their Gynaecologist at least one week prior to their surgery, for 15 minutes who will explain the findings of the scans. They will also attend a review appointment within one month after their surgery with their Gynaecologist. Operation notes will be accessed by the study team after surgery. When consenting for the study, women will also be asked if they are willing to have their contact details including their name, date of birth, address, phone number, email address and treating specialist doctor entered on a secure electronic database and be contacted about future research questions that might arise from this project. It is anticipated that it will take approximately 25 – 35 mins for the participant to complete their baseline data collection. Baseline data collection includes date of birth, height and weight, any previous surgery, any previous diagnostic imaging, Treating Specialist Doctor / Gynaecologist, Surgeon name and Hospital. The observation period will end at the follow up review appointment post surgery.