None listed
Conditions
Brief summary
Dental plaque accumulation is a common problem in toddlers. A randomized controlled trial was conducted to compare the efficacy of CHX gel and PVP-I solution in suppressing dental plaque regrowth in toddlers. The study included forty-five healthy toddlers aged 24-36 months who were randomly assigned to three groups. The first group received a placebo (distilled water (DW)) (negative control). The second group received topical CHX gel (0.2% w/v) (positive control). The third group received topical PVP-I solution (10% w/v). Plaque accumulation was measured at the baseline (t0), after three days (t1), and after 7 days (t2) using the Turesky modified Quigley-Hein plaque index (TMQHPI). Oral hygiene practices were prohibited during the trial period. CHX and PVP-I efficacy lasted only for three days, and PVP-I was not superior to CHX in terms of plaque control in toddlers.
Interventions
The toddlers were randomly assigned to three groups. The first group received a placebo distilled water (negative control). The second group received topical chlorhexidine gel (0.2% w/v) (positive control). The third group received topical povidone iodine solution (10% w/v). The antiplaque agent was applied using a cotton-tipped swab. Plaque accumulation was measured at the baseline (t0), after three days (t1), and after 7 days (t2) using the Turesky modified Quigley-Hein plaque index (TMQHPI).
The toddlers were randomly assigned to three groups. The first group received a placebo distilled water (negative control). The second group received topical chlorhexidine gel (0.2% w/v) (positive control). The third group received topical povidone iodine solution (10% w/v). The antiplaque agent was applied using a cotton-tipped swab. Plaque accumulation was measured at the baseline (t0), after three days (t1), and after 7 days (t2) using the Turesky modified Quigley-Hein plaque index (TMQHPI). Dental plaque was disclosed using the two-tone erythrosine-free plaque disclosing dye solution Mira-2-Ton® (Hager & Werken, Duisburg, Germany). The toddler’s legal guardians were instructed to avoid feeding their child for 30-60 minutes post-antiplaque agent application and oral hygiene practices were prohibited during the trial period. The dose administered: 2 ml. The duration of administration: single application. The mode of administration: topically applied by dentist.
Sponsors
Mawia Karkoutly
Study design
Allocation
Randomised controlled trial
Intervention model
Parallel
Primary purpose
Prevention
Masking
Blinded (masking used) (Investigator, Outcomes Assessor)
Eligibility
Sex/Gender
All
Age
24 Months to 36 Months
Healthy volunteers
Yes
Inclusion criteria
Children aged 24-36 months. Healthy children.
Exclusion criteria
Children with special health care needs (SHCN). Children receiving any antibiotic therapy over the past four weeks. Children with thyroid disorders or iodine allergies. Children with CHX allergies.
Outcome results
None listed