Skip to content

Clinical study to evaluate the effect of Phthalimidoperoxycaproic Acid (PAP) on Vital Teeth Bleaching

Evaluating the Efficacy of Phthalimidoperoxycaproic Acid (PAP) on Vital Teeth Bleaching and Post-Operative Sensitivity: a randomized controlled clinical trial

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ANZCTR
Registry ID
ACTRN12623000553673
Enrollment
17
Registered
2023-05-24
Start date
2023-02-01
Completion date
2023-07-10
Last updated
2023-05-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

A randomized controlled clinical trial aimed to evaluate the effect of Phthalimidoperoxycaproic Acid (PAP) on Vital Teeth Bleaching and post-operative sensitivity, and comparing (PAP) with the gold standard in the at home bleaching 10% carbamide peroxide (CP). The hypothesis of the study is that the Phthalimidoperoxycaproic Acid will be more efficient in vital teeth bleaching and assessed that with low post-operative sensitivity.

Interventions

Vital teeth bleaching using Phthalimidoperoxycaproic acid. The participants will be instructed to apply the bleaching agent (14 days-20min each)(Hismile Pty Ltd., Burleigh Waters, Qld, Australia), delivered by the bleaching custom tray. Participants will be given a post-operative sensitivity sheet to fill in each day of Intervention.

Sponsors

Damascus university
Lead SponsorUniversity

Study design

Allocation
Randomised controlled trial
Intervention model
Parallel
Primary purpose
Treatment

Eligibility

Sex/Gender
All
Age
18 Years to 40 Years
Healthy volunteers
Yes

Inclusion criteria

1-Patient with minimum age 18 years old. 2-Have six anterior maxillary teeth free of restorations and curious lesions. 3-color of the canine A2 or darker in the vita easy shade guide.

Exclusion criteria

1-history of tooth sensitivity. 2-sever internal tooth discoloration 3-pregnant/lactating women 4-smokers 5-using orthodontic appliances 6-previous dental bleaching

Outcome results

None listed

Source: ANZCTR · Data processed: Feb 4, 2026