None listed
Conditions
Brief summary
While continuous positive airway pressure (CPAP) and high flow nasal cannulae (HFNC) are commonly used for treatment of infants with respiratory distress, the optimum level of CPAP/HFNC remains somewhat uncertain. Due to leaks occurring at the nostrils, the mouth and into the stomach, not all of the pressure generated by CPAP/HFNC is transmitted to the airway. Real-time information of the patient’s pharyngeal pressure could provide clinicians with important information. The proposed research is a proof-of-concept observational study to measure the pharyngeal pressure in a convenience sample of 50 infants receiving CPAP/HFNC for the purpose of developing a novel airway pressure monitoring device. TGA-approved dual lumen gastric tubes will be modified to allow for airway pressure measurements in the deep oropharynx using a new airway pressure device (under development). The modified gastric tube will be inserted nasally or orally, similar to regular gastric tubes, and pressures recorded over a one-hour period .
Interventions
In the AIRPREMO Study, a modified TGA approved dual lumen nasogastric tube (initially only 8 French in size; after participant 16, with Ethics Committee approval, either 6 French or 8 French in size, depending on the participant's weight and as per preference of the clinical team) is used to measure deep oropharyngeal air pressure of babies who receive non-invasive respiratory support (either through continuous positive airway pressure or through high flow nasal cannulae). Measurements are obtai
In the AIRPREMO Study, a modified TGA approved dual lumen nasogastric tube (initially only 8 French in size; after participant 16, with Ethics Committee approval, either 6 French or 8 French in size, depending on the participant's weight and as per preference of the clinical team) is used to measure deep oropharyngeal air pressure of babies who receive non-invasive respiratory support (either through continuous positive airway pressure or through high flow nasal cannulae). Measurements are obtained with this research data collection system for up to one hour and data will inform the development of a new device.
Sponsors
Royal Women's Hospital
Eligibility
Sex/Gender
All
Age
0 to 1 Years
Healthy volunteers
No
Inclusion criteria
Babies with a current weight of 1.5 kg or more treated at the Royal Women's Hospital Neonatal Intensive Care Unit receiving non-invasive respiratory support which is expected to be continued for at least one hour who are sufficiently stable for the study intervention as per assessment of the treating neonatal consultant
Exclusion criteria
Weight less than 1.5 kg Anatomical anomaly of the nose, mouth, palate, neck, nasal or pharyngeal airway
Outcome results
None listed