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Evaluation of different approaches to helping people get more out of therapy for non-underweight eating disorders

An adaptive trial design evaluating use of varying wait lists on the severity of disordered eating in people with non-underweight eating disorders

Status
Completed
Phases
Unknown
Study type
Interventional
Source
ANZCTR
Registry ID
ACTRN12623000101684
Acronym
Preparing Ourselves With Early changes to Restriction (POWER)
Enrollment
61
Registered
2023-01-27
Start date
2023-01-24
Completion date
2024-08-30
Last updated
2025-09-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

The primary purpose of the study is to investigate if we can individualise treatment for non-underweight eating disorders in response to initial changes in dietary restriction. We hypothesise that: (1) Single session interventions tackling growth mindset or behavioural activation (both which will reinforce a message of decreasing restriction delivered in assessment) will significantly reduce dietary restriction over a waitlist period before participants receive cognitive behaviour therapy for eating disorders (CBT-ED) compared to a non-suicidal self-injury single session intervention. (2) Those people whose dietary restriction decreases by 50% over the waitlist period and receive the less intensive version of CBT-ED (online guided self-help) will benefit commensurately to those whose dietary restriction does not decrease and who receive a more intensive form of CBT-ED (CBT-T).

Interventions

The initial 90-minute semi-structured interview assessment will be conducted at the Flinders University Services for Eating Disorders clinic by a trainee psychologist. The assessment follows a semi-structured outline, and includes 4 motivational aspects: (1) examining the pros and cons of the eating disorder, (2) examining readiness and confidence to change and barriers to having higher ratings, (3) development of a personalised vicious cycle, and (4) examination of the advantages of change, fea

The initial 90-minute semi-structured interview assessment will be conducted at the Flinders University Services for Eating Disorders clinic by a trainee psychologist. The assessment follows a semi-structured outline, and includes 4 motivational aspects: (1) examining the pros and cons of the eating disorder, (2) examining readiness and confidence to change and barriers to having higher ratings, (3) development of a personalised vicious cycle, and (4) examination of the advantages of change, fears about change, and responses to these fears. The interventions are described and the patient is asked whether they wish to commit to the treatment. People who are suitable and interested to progress will be randomised to one of three 2-week wait-list conditions, single session interventions (SSI) informed by work from Jessica Schleider’s laboratory: growth mindset, behavioural activation and non-suicidal self-injury. All of the SSIs are contained in word documents that the person can do online or in hard copy, and include information and interactive exercises. Participants will be asked to spend 1 hour at the beginning of the 2-week waitlist completing the SSI. Compliance will be assessed using one question about how much was read at the second assessment, and also by the therapist asking them to discuss the last exercise in the SSI with them. The growth mindset SSI contains information about how we can shape our thoughts and feelings by changing our behaviours and the connections in our brains and the importance of nutrition in allowing the brain to adapt. The behavioural activation SSI discusses 4 actions that can improve mood: (1) Connecting with people who make you feel good; (2) Achieving goals that matter to you; (3) Enjoying activities on your own; (4) Feeding your brain. The non suicidal self-injury SSI discusses techniques for ceasing cease self-harming behaviours. Those participants who decrease restriction (assessed using the dietary restriction subscale of the Eating Disorder Examination Questionnaire) by 30% at the end of the 2-week waitlist will be allocated to an online guided 10-session CBT-ED delivered weekly with therapist contact for 30-50 minutes each week. Those who show less response will be allocated face-to-face 10-session CBT-T, offered weekly for 50 minutes each session. The main difference between these two forms of CBT are that CBT-T includes a large component of body image work, while the online CBT focuses more on time on motivation. This approach is informed by a very consistent and large body of research showing that early response is the strongest and most consistent predictor of good outcome, and that people with non-underweight eating disorders who experience this early change do well with guided self-help CBT-ED. For each form of CBT the therapist is a postgraduate Clinical Psychology trainee, provisionally registered. Adherence to sessions will be monitored by attendance at sessions, whether online or face-to-face.

Sponsors

Flinders University
Lead SponsorUniversity

Study design

Allocation
Randomised controlled trial
Intervention model
Parallel
Primary purpose
Treatment
Masking
Open (masking not used)

Eligibility

Sex/Gender
All
Age
15 Years to No maximum
Healthy volunteers
No

Inclusion criteria

(1) age 15 years and above; (2) body mass index greater than or equal to 18.5; (3) a DSM-5 eating disorder diagnosis excluding binge eating disorder; and (4) involvement of the general practitioner.

Exclusion criteria

substance dependence, active psychosis, high suicidality, or difficulty understanding or speaking English

Outcome results

None listed

Source: ANZCTR · Data processed: Feb 4, 2026