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Chest x-ray versus low dose high resolution computed tomography in screening Queensland workers for occupational dust lung disease.

A study comparing the diagnostic accuracy of the current imaging method for screening of occupational lung diseases in dust-exposed workers (International Labour Organization (ILO) chest x-ray (CXR)) to low-dose high resolution computed tomography (LD HRCT).

Status
Not yet recruiting
Phases
Unknown
Study type
Observational
Source
ANZCTR
Registry ID
ACTRN12623000054617
Enrollment
500
Registered
2023-01-17
Start date
2023-01-23
Completion date
2025-07-31
Last updated
2023-01-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

This study is a comparative study investigating how ILO chest x-ray compares to low dose high resolution computed tomography (LD HRCT) for early diagnosis of occupational lung disease. As part of this study participants will be asked to undergo a LD HRCT scan, which is new technology using very low levels of radiation. HRCT scans are better at diagnosing early stage of occupational lung diseases than chest radiography. This study will answer the question about whether the low radiation dose HRCT scan used in this study picks up more early stage lung diseases such as black lung, emphysema and silicosis. No Australian evidence has been collected to demonstrate the use the use of LD HRCT in the screening of occupational lung diseases.

Interventions

The research intervention is a single low dose (LD) high resolution computed tomography (HRCT) scan (non-contrast). The LD HRCT scan will be done in a fully accredited imaging clinic by an accredited radiologist. There is no dye injection, and no special preparation required. The scan is performed within a CT scan machine, and takes less than 15 minutes. The participant will be asked to breathe in and out for different scan images. The CT scan can be performed on the same day as the workers

The research intervention is a single low dose (LD) high resolution computed tomography (HRCT) scan (non-contrast). The LD HRCT scan will be done in a fully accredited imaging clinic by an accredited radiologist. There is no dye injection, and no special preparation required. The scan is performed within a CT scan machine, and takes less than 15 minutes. The participant will be asked to breathe in and out for different scan images. The CT scan can be performed on the same day as the workers standard care International Labour Organisation chest x-ray (ILO CXR) or within 3 months of their ILO CXR (to fulfill inclusion criteria). No further radiological and/or clinical investigation will be undertaken as part of this study.

Sponsors

I-MED Radiology Network
Lead SponsorCommercial sector/Industry

Eligibility

Sex/Gender
All
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

• Minimum of 18 years of age • Work/have worked in Queensland industry (i.e. coal mine, hard rock mine, quarry and other respirable crystalline silica-exposed work) • Have at least ten years of occupational dust exposure (coal mine dust or respirable crystalline silica) • Be undergoing an occupational health assessment that includes an ILO CXR

Exclusion criteria

• Engineered stone-exposed stonemasons or history of exposure to engineered stone products • Patients with an existing diagnosis of coal workers pneumoconiosis or silicosis • Patients undergoing ILO CXR for ongoing medical management of disease diagnosed or suspected through previous occupational screening assessment • Patients with a CT chest study obtained and available to review within the preceding 6 months • Pregnant or breastfeeding mothers

Outcome results

None listed

Source: ANZCTR · Data processed: Feb 4, 2026