Association Of Serum Lipid Profile With Acne Vulgaris In Pakistani Population

Serum lipid levels Serum lipid profiles will be tested at presentation only once after an overnight fast of 12 hours to quantify total cholesterol (TC), HDL-C, LDL-C, and triglycerides (TG). The lipid profile will be done on Atellica system using photometric principle. Serum LDL will be estimated using Friedewald's formula The normal ranges for the serum lipid profile are based on the National Cholesterol Education Program Adult Treatment Panel III (NCEP ATP III) Dyslipidemia: National Cholesterol Education Programme (NCEP) guidelines 11 will be used for definition of dyslipidemia as follows Total Cholesterol normal range <5 2 mmol/L . Hypercholesterolemia serum cholesterol levels greater than or equal to 200 mg/dl (greater than or equal to 5.2 mmol/l) Triqlvcerides normal range <150 mg/dl Hypertriglyceridemia - serum triglyceride levels greater than or equal to 150 mg/dl (greater than or equal to 1.7 mmol/l) HDL-C normal range HDL cholesterol levels >40 mg /dl low HDL lesser than 40 mg/dl (lesser than 1.04 mmol/l) LDL-C normal range LDL cholesterol levels <130mg/dl Raised serum LDL -C greater than or equal to 130 mg/dl (greater than or equal to 3.4 mmol/l) calculated using the Friedewald equation High total cholesterol to HDL-C ratio A TC/HDL-C ratio raised beyond 4.0 will be characterized as a marker of deranged lipid profile Cases with clinical findings of acne vulgaris will be graded according to Global Acne Grading System Score (GAGS score) into mild moderate and severe acne on their visit to outpatient department