None listed
Conditions
Brief summary
Anaemia is a common problem worldwide. In the perioperative setting, it has been identified as a predictor of morbidity and mortality in both adults and children. Anaemic patients undergoing surgery often require transfusion of autologous blood products in the perioperative period, which carries both a risk of morbidity and increased healthcare costs. For these reasons, patient blood management programmes have been developed internationally which emphasise diagnosis and treatment of preoperative anaemia with the aim of improving outcomes and reducing costs in the adult surgical population. The prevalence of preoperative anaemia in the paediatric surgical population is poorly described in the literature, and the current prevalence of anaemia in children undergoing major elective surgery in New Zealand is unknown. Some pathologies requiring major surgery in children disproportionately affect groups at higher risk of anaemia, such as postmenarchal adolescent females undergoing surgical correction of idiopathic scoliosis. Recent studies suggest that anaemia in the general paediatric population in New Zealand is common, and disproportionately affects those of Maori and Pacific ethnicity. A better understanding of preoperative anaemia as a clinical entity in the paediatric surgical population in New Zealand will allow an opportunity to improve quality of clinical care, and develop strategies to target any inherent inequities in our current system. This study aims to: - Quantify the prevalence of preoperative anaemia in paediatric patients undergoing major surgery. - Investigate the subtypes of anaemia in those patients identified as being anaemic. - Identify differences in preoperative anaemia prevalence between different ethnic groups. - Identify differences in preoperative anaemia prevalence between surgical disciplines. - Describe the association between preoperative anaemia and transfusion of blood products. - Investigate the association between preoperative anaemia and patient morbidity and mortality.
Interventions
This is a retrospective observational study to determine the prevalence of anaemia (as defined by the World Health Organisation) in paediatric patients undergoing elective or emergency major surgery in a single tertiary centre in New Zealand.
Medical records for all patients undergoing major surgery between 01/01/2021 and 01/01/2022 will be analysed, and those with a full blood count within 3 months prior to surgery recruited. As well as haemoglobin concentration prior to surgery, researchers w
This is a retrospective observational study to determine the prevalence of anaemia (as defined by the World Health Organisation) in paediatric patients undergoing elective or emergency major surgery in a single tertiary centre in New Zealand. Medical records for all patients undergoing major surgery between 01/01/2021 and 01/01/2022 will be analysed, and those with a full blood count within 3 months prior to surgery recruited. As well as haemoglobin concentration prior to surgery, researchers will collect ferritin concentration, creatinine concentration, folate/B12 concentration, gender, age, weight, ethnicity, ASA score, surgical priority, type of surgery, the presence of significant comorbidities, intraoperative and postoperative blood transfusions, length of stay in hospital, and 30 day mortality. Data collected for each participant will pertain to a single admission episode.
Sponsors
Department of Anaesthesia, Starship Children's Hospital
Eligibility
Sex/Gender
All
Age
6 Months to 15 Years
Healthy volunteers
No
Inclusion criteria
All patients > 6 months and < 16 years undergoing major surgery between 01/01/2021 at 01/01/2022.
Exclusion criteria
Age < 6 months or > 16 years. Blood transfusion within 7 days prior to surgery. No preoperative haemoglobin concentration available in the 3 month period prior to surgery.
Outcome results
None listed