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Comparative study of the effects of cardiac rehabilitation on autonomic, hemodynamic, metabolic and physical condition parameters among subjects submitted to percutaneous revascularization and bypass due to Acute Coronary Syndrome.

Comparative study of the effects of cardiac rehabilitation on autonomic, hemodynamic, metabolic and physical condition parameters among subjects submitted to percutaneous revascularization and bypass due to Acute Coronary Syndrome.

Status
Completed
Phases
Unknown
Study type
Interventional
Source
ANZCTR
Registry ID
ACTRN12622001491752
Enrollment
34
Registered
2022-11-29
Start date
2022-06-11
Completion date
2023-03-10
Last updated
2024-04-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

Introduction: physical exercise within cardiac rehabilitation processes has shown a 20-25% reduction in total and cardiovascular mortality when compared to rehabilitation that does not include this type of treatment. On the other hand, the differences in their effectiveness for subjects with percutaneous revascularization and coronary bypass is not clear. Objective: To compare the effects of cardiac rehabilitation on autonomic, hemodynamic, metabolic and physical capacity parameters among subjects undergoing percutaneous revascularization and coronary bypass for acute coronary syndrome (ACS). Methods: Quasi-experimental study conducted in 58 subjects undergoing percutaneous coronary revascularization (n=29) and cardiac bypass (n=29). All will be evaluated at the beginning of the protocol and after 12 weeks of aerobic training within a cardiac rehabilitation program (phase II), with a frequency between 3 to 5 sessions per week and a duration of 60 minutes per session at an intensity of 50% to 70%. Heart Rate Reserve (HRF) or perception of exertion (Modified Borg3/6). The variables evaluated will be: cardiorespiratory capacity, heart rate variability, lipid profile (total cholesterol, triglycerides) and glycemia. Expected results: This work presents the opportunity to identify differences in the scope of physical exercise protocols included in phase II cardiac rehabilitation programs, on functional physical capacity, hemodynamic, metabolic and cardiovascular autonomic variables in subjects undergoing percutaneous revascularization and coronary bypass for ACS. This would support the need to continue or adjust the programs used in the institutions that provide these rehabilitation services. The hypotesis is that Person with percutaneous revascularization will have bigger Heart Rate Variability, because by the heart manipulation in coronary bypass, is altered autonomic modulation

Interventions

Intervention will commence after inpatient discharge. In the outpatient cardiac rehabilitation center Patient with coronary bypass who will received 12 consecutive weeks of physical training, with a frequency of 3 days per week, 60 minutes per session, consisting on: 5 minutes of warm-up, 40 minutes of work in treadmill and cycloergometer, and a 5-minute cool down. An intensity between 50% and 70% of the reserve heart rate or 3-6 in the modified Borg scale. In addition, two sessions per week o

Intervention will commence after inpatient discharge. In the outpatient cardiac rehabilitation center Patient with coronary bypass who will received 12 consecutive weeks of physical training, with a frequency of 3 days per week, 60 minutes per session, consisting on: 5 minutes of warm-up, 40 minutes of work in treadmill and cycloergometer, and a 5-minute cool down. An intensity between 50% and 70% of the reserve heart rate or 3-6 in the modified Borg scale. In addition, two sessions per week of resistance training in upper extremities with moderate intensity (3-5 modified Borg) in this days the patient will receive 10 minutes of resistant training whit elastic bands of different resistances 4 sets of 8 - 10 reps 3 or 4 exercises like shoulder abduction, elbow flexion and extension and so on, this days the session will take 10 more minutes. The intervention will be delivered by a specialized physiotherapist in cardiopulmonary, and it will be provided individually. Each day the patient will sign an attendance registry which contents the follow up.

Sponsors

Profesionales de la Salud Ltda.
Lead SponsorOther Collaborative groups

Study design

Allocation
Non-randomised trial
Intervention model
Other
Primary purpose
Treatment
Masking
Open (masking not used)

Eligibility

Sex/Gender
All
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

Subjects over 18 years, residing in Bucaramanga during the study and who are referred to a cardiac rehabilitation program-Phase II, after having undergone percutaneous or bypass revascularization for a first coronary event.

Exclusion criteria

- Patients who have absolute or relative contraindications for the performance of physical exercise or the functional capacity test. -Subjects with ejection fraction <40%. -Patients with pacemaker implantation. -Patients with diagnosed arrhythmias.

Outcome results

None listed

Source: ANZCTR · Data processed: Feb 4, 2026